Evidence map›Paper›PMID 42181266›Full record

ArticleiScience2026

Strong concordance of DNA methylation measures between venous and capillary blood - Implications for human epigenome studies.

Hannah-Ruth Engelbrecht, Chaini Konwar, Beryl C Zhuang, Kristy Dever, Julie L MacIsaac, Thomas W McDade, Tran Khanh Toan, Kim Korinek, Zachary Zimmer, Michael S Kobor

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in iScience, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Hannah-Ruth EngelbrechtBC Children's Hospital Research Institute, Vancouver, BC V5Z 4H4, Canada.
Chaini KonwarBC Children's Hospital Research Institute, Vancouver, BC V5Z 4H4, Canada.
Beryl C ZhuangBC Children's Hospital Research Institute, Vancouver, BC V5Z 4H4, Canada.
Kristy DeverBC Children's Hospital Research Institute, Vancouver, BC V5Z 4H4, Canada.
Julie L MacIsaacBC Children's Hospital Research Institute, Vancouver, BC V5Z 4H4, Canada.
Thomas W McDadeDepartment of Anthropology, Northwestern University, Evanston, IL 60201, USA.
Tran Khanh ToanFamily Medicine Department, Hanoi Medical University, Hanoi, Vietnam.
Kim KorinekDepartment of Sociology, University of Utah, Salt Lake City, UT 84112, USA.
Zachary ZimmerDepartment of Family Studies and Gerontology, Mount Saint Vincent University, Halifax, NS B3M 1P5, Canada.
Michael S KoborBC Children's Hospital Research Institute, Vancouver, BC V5Z 4H4, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

DNA methylation (DNAm) is influenced by the tissue composition, which can be attributed to cellular heterogeneity. Venous and capillary blood are common blood sources in human studies, but may have differences in their cell type composition and resulting DNAm profiles. Using the Illumina EPIC v2 microarray, we compared matched (

Indexed as

EpigeneticsGenomics

Identifiers

PMID42181266
PMCPMC13197641

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.