ArticleClinical and translational radiation oncology2026
Chronotype-based radiotherapy in localised prostate cancer: protocol for a prospective cohort integrating MCTQ and salivary DLMO.
Article in Clinical and translational radiation oncology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
10 authors.
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Abstract
We present a prospective observational cohort protocol evaluating whether chronotype-based radiotherapy timing reduces treatment-related toxicities in localised prostate cancer. Individual circadian phase is characterised using the Munich ChronoType Questionnaire and salivary dim-light melatonin onset. The primary endpoint is late genitourinary toxicity grade ≥2 at 12 months, with secondary endpoints including gastrointestinal toxicity and patient-reported outcomes. The protocol is conducted at IPO Porto and designed for multi-site adoption.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.