ArticleMethodsX2026
Simplified synthesis of anti-oxidant small molecule
Article in MethodsX, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
3 authors.
Funding
Abstract
We have designed a short, improved synthetic strategy for the synthesis of a multi-tactical anti-oxidant small macrocycle molecule. The overall simplified 6-step synthetic scheme gave a chemical yield of 45.7 % compared to the previously reported strategy of 22.4 %. The synthesis of the macrocycle started with esterification of chelidamic acid through a series of reactions, including Richman-Atkins macrocyclization, and ends with global deprotection of compound
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.