ArticleMethodsX2026
Lactose quantification in human breast milk by gas chromatography - mass spectrometry.
Article in MethodsX, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Mammary gland development is a complex process that begins in utero and continues to evolve after birth and throughout life. During and after pregnancy, this gland responds to stimuli to prepare for reproduction, undergoing several cycles of growth, maturation, milk production and secretion, and finally involution. Lactation is a high-energy-consuming process that, over a limited period, becomes one of the major energy expenditures for mothers, which is essential for the offspring's survival. The mammary epithelium produces and secretes the different milk constituents, consisting of protein, lipids, and carbohydrates (lactose). Lactose represents one of the most abundant nutrients present in milk, being of the utmost importance for newborns. Here, we present a new methodology to perform quantitative measurement of lactose by gas chromatography - mass spectrometry. The method is simple and allows high recovery of lactose (>95%), along with a high reproducibility between batches at physiologically relevant concentrations. It thus represents a new tool to further study milk biology.•A novel protocol to measure lactose by mass spectrometry in milk is described.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.