Evidence map›Paper›PMID 42181030›Full record

ReviewEndocrine oncology (Bristol, England)2026

A contemporary overview of multiple endocrine neoplasia syndromes: MEN syndromes 1-5 and beyond.

Raquel A Maggacis, Alexandra Sorvina, Lisa J Hayes, Warrick J Inder, Emily K Brooks, Sunita M C De Sousa

Abstract readReview
In one paragraph

Review in Endocrine oncology (Bristol, England), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Raquel A MaggacisDiabetes and Endocrinology, Princess Alexandra Hospital, Brisbane, Queensland, Australia.ORCID https://orcid.org/0000-0002-5085-6996
Alexandra SorvinaCentre for Cancer Biology, An Alliance Between South Australia Pathology and The University of South Australia, Adelaide, South Australia, Australia.
Lisa J HayesDiabetes and Endocrinology, Princess Alexandra Hospital, Brisbane, Queensland, Australia.
Warrick J InderDiabetes and Endocrinology, Princess Alexandra Hospital, Brisbane, Queensland, Australia.
Emily K BrooksDiabetes and Endocrinology, Princess Alexandra Hospital, Brisbane, Queensland, Australia.
Sunita M C De SousaUniversity of Adelaide, Adelaide, South Australia, Australia.ORCID https://orcid.org/0000-0003-0127-6482

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Multiple endocrine neoplasia (MEN) syndromes constitute a heterogeneous group of hereditary disorders predisposing to endocrine tumours of varying malignant potential. Recent advances in molecular genetics and tumour biology have significantly reshaped our understanding of underlying pathophysiology, enabling earlier diagnosis, genotype-specific surveillance and the emergence of targeted therapies. This review provides a contemporary overview of key recent advances and consensus guidelines across MEN syndromes, including MEN1, MEN2, MEN4, and MEN5 syndromes, SDHx syndrome, Carney complex, McCune-Albright syndrome, DICER1 syndrome and von Hippel-Lindau syndrome. These insights reflect a rapidly evolving field with genetic diagnosis at the centre of prognostic assessment, targeted surveillance and individualised management.

Indexed as

molecular geneticsmultiple neuroendocrine neoplasianeuroendocrine tumours

Identifiers

PMID42181030
PMCPMC13193063

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.