ArticleTranslational cancer research2026
Digitoxin inhibits the growth of HSC-3 cells by inducing G2/M cell cycle arrest and apoptosis.
Article in Translational cancer research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Oral squamous cell carcinoma (OSCC) remains a substantial global health burden. According to the latest global cancer statistics, it accounts for an estimated 300,000 new cases and 100,000 deaths annually. This study aimed to investigate the pharmacological effects of digitoxin, a cardenolide glycoside, on the modulation of proliferative capacity and apoptotic induction in human OSCC human tongue squamous carcinoma (HSC-3) cells. Methods: Results: Digitoxin treatment reduced the viability of HSC-3 cells in a concentration-dependent manner and concurrently increased the apoptotic fraction. Mechanistically, digitoxin induced G Conclusions: Digitoxin inhibited the growth of HSC-3 cells both
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.