ArticleFrontiers in medicine2026
Low-dose rocuronium as an adjuvant to remifentanil for laryngeal mask airway-assisted flexible fiberoptic bronchoscopy in children: protocol for a randomized placebo-controlled trial.
Article in Frontiers in medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: Flexible fiberoptic bronchoscopy is being increasingly carried out under general anesthesia in pediatric patients. However, the optimal anesthetic protocol still remains unclear. This study aims to test the hypothesis that the addition of low-dose rocuronium during laryngeal mask airway-assisted flexible fiberoptic bronchoscopy in children can enhance procedural outcomes and improve overall management. Methods: In this randomized, double-blind, placebo-controlled trial, 140 children aged 1-6 years scheduled for flexible fiberoptic bronchoscopy under general anesthesia will be randomly allocated in a 1:1 ratio to either the rocuronium group or the normal saline group ( Discussion: We hypothesize that the addition of low-dose rocuronium during laryngeal mask airway-assisted flexible fiberoptic bronchoscopy under general anesthesia may optimize operation conditions, reduce coughing frequency, lower remifentanil dosage and the failure rate, stabilize hemodynamic fluctuations, minimize adverse events and enhance satisfaction, thereby providing valuable reference for clinical anesthesia practice in these procedures. Study Protocol Registration: https://www.chictr.org.cn/showprojEN.html?proj=277486, identifier [ChiCTR2500105407].
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