ArticleFrontiers in medicine2026
Changes in anterior segment parameters after laser peripheral iridotomy in patients with primary angle closure suspect.
Article in Frontiers in medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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9 authors.
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Abstract
Objective: To evaluate changes in anterior segment parameters before and after laser peripheral iridotomy (LPI) in patients with primary angle closure suspect (PACS), analyze the role of anterior chamber anatomical changes in the development of primary angle closure glaucoma (PACG), and assess the clinical value of LPI in PACS. Method: A total of 42 patients (42 eyes) diagnosed with PACS and treated with LPI at the Ophthalmology Department of Shaoxing People's Hospital between January 2023 and April 2025 were included. Anterior chamber volume (ACV), anterior chamber depth (ACD), and anterior chamber angle (ACA) were measured using the Sirius anterior segment analysis system before surgery and at 1 week and 3 months postoperatively. Visual acuity, intraocular pressure, and corneal endothelial cell density were also assessed. Comparisons among time points were performed using SPSS 25.0, with Result: This study included 7 males and 35 females aged 41-84 years (mean age, 62.62 ± 9.50 years), with a mean axial length of 22.09 ± 0.82 mm. There were no significant differences in visual acuity or intraocular pressure across the three time points ( Conclusion: LPI in patients with PACS is safe, as it does not adversely affect visual acuity, intraocular pressure, or corneal endothelial cell density. The procedure significantly deepens the anterior chamber, increases ACV, and widens the ACA, supporting its role in improving anterior segment anatomy and potentially delaying progression to primary angle closure and PACG.
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