ArticleFrontiers in medicine2026
Taste aversion as an under-recognized determinant of bowel preparation quality.
Article in Frontiers in medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Abstract
Inadequate bowel preparation remains a major barrier to high-quality colonoscopy, with taste aversion representing a common yet under-recognized contributor to poor tolerability of the bowel preparation. Current strategies primarily aim to improve palatability through formulation changes or dosing regimens. This paper proposes a novel, hypothesis-driven approach: transient pharmacologic suppression of gustatory perception using topical oral lidocaine to reduce the perceived unpleasantness of bowel preparation solutions. The concept arises from a serendipitous clinical observation in which tongue-focused lidocaine application enabled successful oral intake in a patient with repeated prior intolerance. By targeting taste perception directly rather than modifying the preparation itself, this approach may offer a complementary strategy for selected patients. Further evaluation is required to assess feasibility, safety, and clinical effectiveness.
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