Translation, cross-cultural adaptation and validation of the Chinese version of irritable bowel syndrome severity scoring system.

Objective: Given that the Irritable Bowel Syndrome Severity Scoring System (IBS-SSS) is widely utilized in IBS-related clinical research but lacks an officially approved Chinese version (IBS-SSS-C), which has impeded its application in Chinese research contexts. This study aims to translate and cross-culturally adapt the IBS-SSS into a Chinese version, and validate its key properties, thereby developing a reliable and officially recognized tool for assessing IBS severity among the Chinese population. Methods: We obtained translation permission for the IBS-SSS from the Rome Foundation, and translated and cross-culturally adapted it into a Chinese version according to the official guideline. Validation was performed as clinical trials assessing responsiveness to change ( Results: Through forward and backward translation, and cross-cultural adaption, the IBS-SSS-C was developed and approved for use by the Rome Foundation. A significance difference in the absolute change of the IBS-SSS-C total score before and after treatment was found in the AR responder and non-responder groups ( Conclusion: Our findings indicate that the IBS-SSS-C appears to be a reliable and appropriate instrument for IBS outcome assessment in the Chinese population; nevertheless, further validation in larger-scale, multi-center studies is required.