ArticleFrontiers in medicine2026
The predictive value of preoperative clinical laboratory indicators combined with sarcopenia for postoperative complications of gastric cancer.
Article in Frontiers in medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: Postoperative complications (POCs) significantly affect recovery and prognosis in patients with gastric cancer. This retrospective cohort study aimed to develop and validate a nomogram integrating preoperative clinical laboratory indicators and sarcopenia to predict POCs in patients undergoing radical gastrectomy. Method: A retrospective analysis was conducted on 181 patients who underwent radical gastrectomy for gastric cancer between October 2019 and June 2022. Patients were randomly assigned to a training set ( Results: Inter-observer consistency for SMI measurement was excellent (intraclass correlation coefficient [ICC] = 0.86). Univariate analysis revealed that clinical N stage, carcinoembryonic antigen (CEA) level, sarcopenia, and CT-assessed serosal invasion were significantly associated with POCs (all Conclusion: The nomogram integrating preoperative CEA, sarcopenia, CT-assessed serosal invasion, and clinical N stage effectively predicts the risk of postoperative complications in gastric cancer patients, facilitating preoperative risk stratification and personalized perioperative management.
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