ArticleFrontiers in medicine2026
Objective pulse wave amplitude as a potential systemic correlate in childhood myopia: a digital TCM-based study.
Article in Frontiers in medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: Childhood myopia is increasingly recognized as a condition with systemic underpinnings, aligning with the holistic perspective of Traditional Chinese Medicine (TCM). This study aimed to explore associations between childhood myopia and objectively measured TCM pulse, tongue, and face diagnostic parameters using digital instruments. Methods: In this cross-sectional, school-based study, 873 children aged 7-14 years from Shandong Province, China, underwent comprehensive examinations. Myopia was defined as a cycloplegic spherical equivalent (SE) ≤ -0.50 D. Objective parameters of pulse (using the DS01-DI pulse diagnosis instrument), tongue, and face (using the DS01-B system) were automatically acquired. Associations with myopia, SE, and axial length (AL) were evaluated using multivariable logistic regression and generalized linear models, adjusting for age, sex, BMI, parental myopia, time spent on near work and outdoor activities, and TCM body constitution. Results: Among 873 children, 464 (53.15%) had myopia. After covariate adjustment, the amplitude of the main pulse wave (h1) was independently and negatively associated with myopia in all children (Model 1: OR = 0.834, Conclusion: Reduced h1 amplitude is a systemic correlate of childhood myopia, whereas tongue and facial features showed no significant associations. These findings support the potential of pulse-based systemic assessment in integrated myopia research.
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