ArticlePeerJ2026
Predictive value of calf circumference, prealbumin, and serum calcium for 28-day mortality in male sepsis patients with nutritional risk: a retrospective study.
Article in PeerJ, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: Sepsis is a life-threatening organ-dysfunction syndrome driven by infection. A substantial proportion of septic patients present with nutritional risk, a combination that worsens prognosis. Easily accessible early prognostic tools for this high-risk subset are lacking. Objective: To identify early risk factors for 28-day clinical death in sepsis patients with nutritional risk. Methods: A retrospective analysis of sepsis patients in the intensive care unit (ICU) at the Affiliated Hospital of Inner Mongolia Medical University (Jan 2022 to Jan 2025). Patients were categorized by 28-day outcome. Univariate and multivariate logistic regression identified risk factors; receiver operating characteristic (ROC) curves evaluated predictive performance. Results: Among 231 patients, 154 were male (mortality 13.0%) and 77 female (mortality 11.7%). In males, multivariate analysis identified calf circumference, serum prealbumin (PA), and serum calcium (Ca Conclusions: Calf circumference, PA, and Ca
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