ArticleFrontiers in public health2026
Effects of noise exposure and long working hours on oxidative stress levels and high-frequency hearing threshold damage in occupational populations.
Article in Frontiers in public health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Introduction: Occupational noise-induced hearing loss remains a significant public health concern in China. This study aimed to investigate the associations between combined exposure to occupational noise and long working hours with oxidative stress levels and high-frequency hearing loss (HFHL) in an occupational population. Methods: A total of 547 Chinese workers from eight manufacturing enterprises in Guangzhou who were engaged in noise-exposed occupations were recruited. Participants were divided into a noise exposure group (weekly working hours ≤40 h, Results: The study included 532 males (97.3%) and 15 females (2.7%). Compared with the noise exposure group, the combined exposure group presented significantly lower SOD activity and CAT activity ( Conclusion: Combined exposure to noise and long working hours is associated with exacerbated oxidative stress and high-frequency hearing loss in occupational populations. CAT acts as an independent protective factor against HFHL, suggesting its potential as a biomarker for hearing damage assessment, although prospective validation is needed.
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