Evidence map›Paper›PMID 42180239›Full record

ArticleFrontiers in neurology

An explainable streaming early identification model for early neurological deterioration based on coordinated fusion of ECG waveforms and vital signs.

Yuyan Zhang, Shihan Yao, Bo Wen, Jinjie Liu

Abstract read
In one paragraph

Article in Frontiers in neurology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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5 · Who and what money

Authors and funding

4 authors.

Yuyan ZhangSchool of Computer and Communication Engineering, University of Science and Technology Beijing, Beijing, China.
Shihan YaoSchool of Computer and Communication Engineering, University of Science and Technology Beijing, Beijing, China.
Bo WenSchool of Computer and Communication Engineering, University of Science and Technology Beijing, Beijing, China.
Jinjie LiuDepartment of Neurology, Central Hospital of Dalian University of Technology, Dalian, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Endovascular treatment (EVT) has emerged as a cornerstone in the clinical management of stroke. However, postoperative Early Neurological Deterioration (END) persists as a formidable challenge, frequently correlating with long-term disability and poor prognosis. Consequently, timely and accurate prediction of END is imperative for guiding early clinical intervention and improving patient outcomes. This study introduces DSF-Net, a cost-sensitive, dual-stream multimodal framework engineered for the continuous postoperative monitoring of stroke patients. The architecture leverages a dual-stream design: the first stream employs a 1D convolutional neural network (1D-CNN) to extract latent representations from high-frequency physiological waveforms, while the second stream utilizes a multilayer perceptron (MLP) to encode structured clinical indicators. These fused representations are subsequently processed by a Transformer encoder to capture complex temporal dependencies within granular monitoring windows. To mitigate the challenges posed by extreme class imbalance (i.e., the scarcity of END-positive instances), we integrate cost-sensitive learning with a dynamic threshold optimization strategy prioritized for F1-score maximization. Experimental results demonstrate that DSF-Net achieves superior predictive performance on postoperative monitoring datasets, yielding an Area Under the Curve (AUC) of 0.9996 and an F1-score of 0.9841. Notably, with the optimized threshold, the model enhances the END recall rate to 99%, a significant improvement over the 74% achieved by a conventional LSTM baseline. Furthermore, interpretability analysis using Integrated Gradients (IG) reveals that the model can identify subtle morphological variations in waveforms preceding deterioration, thereby facilitating transparent and actionable early warnings. These findings suggest that DSF-Net provides a robust and interpretable solution for intelligent monitoring in post-stroke care.

Indexed as

cost-sensitive learningearly neurological deterioration (END)intelligent monitoringischemic strokemultimodal fusiontransformer

Identifiers

PMID42180239
PMCPMC13189961

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.