ArticleFrontiers in oncology2026
A case report of acute carcinoid heart failure during lutetium-177 dotatate-triapine treatment for well-differentiated neuroendocrine tumors.
Article in Frontiers in oncology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Introduction: Well-differentiated neuroendocrine tumors (NETs) have a high indolent local progression rate when resistance develops to biologic or cytotoxic chemotherapy. Radiopharmaceuticals like single-agent [ Case presentation: The patient, a 69-year-old man with gastroenteropancreatic NET with liver metastases and known chronic systolic heart failure (HF), had received octreotide then everolimus therapy prior to enrollment. At entry, his disease status was complicated by bilateral edema to his thighs worsening over a 4-week period and an echocardiogram showing right heart hypertrophic cardiomyopathy with an ejection fraction of 40%. [ Conclusion: This case reports the rare complication of an acute exacerbation of carcinoid-associated HF by the [
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