ArticleFrontiers in oncology2026
A volume-controlled, anatomy-driven autoplanning strategy for whole-pelvic volumetric modulated arc therapy.
Article in Frontiers in oncology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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4 authors.
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Abstract
Background and purpose: Whole pelvic radiotherapy (WPRT) involves volumetric modulated arc therapy (VMAT) planning that requires careful consideration of target coverage and organ-at-risk (OAR) sparing. Manual planning is labor-intensive and subject to inter-planner variability. To address these challenges, we developed and evaluated a Volume-Controlled Autoplan (VCAP), an anatomy-driven automated planning strategy that incorporates volumetric overlap information into the optimization framework. Materials and methods: This study retrospectively analyzed a cohort of patients with pelvic malignancies who underwent WPRT. VCAP was compared against clinical planning (CP), Autoplan (AP), and RapidPlan (RP). Dosimetric endpoints included PTV coverage (V Results: VCAP achieved comparable PTV coverage relative to CP, AP, and RP, with V Conclusion: VCAP provides an efficient and anatomy-driven approach to VMAT planning for WPRT. By incorporating volumetric overlap constraints into the optimization process, VCAP enhances OAR sparing while preserving robust PTV coverage. These findings suggest that VCAP may improve planning efficiency and consistency in clinical practice. Further validation is warranted to assess its generalizability and potential role in broader clinical applications.
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