ArticleKidney medicine2026
Psychosocial Health and Quality of Life Among Living Kidney Donors: A Study From a Tertiary Care Center in South India.
Article in Kidney medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Rationale & Objectives: Although kidney donation has been deemed a safe procedure with low mortality and morbidity, the impact of organ donation on the long-term quality of life is not known in our population. We aimed to compare the quality of life between age and sex-matched living kidney donors and healthy nondonors and to estimate the prevalence of anxiety, depression, and regret among kidney donors. Study Design: Questionnaire-based observational study. Setting & Participants: Adult living kidney donors aged ≥18 years who donated between 2020 and 2024 at a tertiary care center in South India. Predictors: We analyzed the effects of baseline clinical, sociodemographic factors, postoperative complications, long-term comorbid conditions, and recipient and donor renal function on the psychosocial health of living kidney donors. Outcomes: Quality of life and the prevalence of anxiety, and depression were determined using the SF-36 (36-Item Short Form Health Survey), General Anxiety Disorder-7 (GAD-7), and Patient Health Questionnaire-9 (PHQ-9), respectively. Results: Of the 69 included living kidney donors, 57 (82.6%) were female. Post-donation anxiety and depression were seen in 7 (10.1%) donors and 3 (4.3%) donors, respectively. The SF-36 Mental Component Summary and Physical Component Summary scores of donors were not statistically different from those of age- and sex-matched healthy donors (46.84 ± 8.72 vs 48.48 ± 7.52; Limitations: The study was conducted at a single center with a relatively small sample size. Conclusions: The quality of life of kidney donors was comparable to that of healthy nondonors except for a subgroup of donors older than 50 years who had worse quality of life parameters in certain domains compared with younger donors. Overall, living kidney donors reported a positive donation experience, with low rates of regret.
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