Evidence map›Paper›PMID 42179683›Full record

ArticleJournal of circulating biomarkers

VEGF, TNF-α, and PCT efficiency for traumatic brain injury prognosis evaluation in the first 72 h.

Diya Hasan, Ola M Al-Sanabra, Mutaz Jamal Al-Khreisat, Ghaith H Mansour, Tareq Nayef AlRamadneh, Moath Alqaraleh, Alqassem H Abuarqoub, Ahmad Al Tibi, Mu'ad Al-Zu'abe, Sara Abaza

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Article in Journal of circulating biomarkers. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Diya HasanDepartment of Allied Medical Sciences, Zarqa College, Al-Balqa Applied University, Zarqa - Jordan.
Ola M Al-SanabraDepartment of Medical Laboratory Sciences, Faculty of Allied Medical Sciences, Al-Balqa Applied University, Al-Salt - Jordan.
Mutaz Jamal Al-KhreisatDepartment of Medical Laboratory Sciences, Faculty of Allied Medical Sciences, Al-Ahliyya Amman University, Amman - Jordan.
Ghaith H MansourDepartment of Allied Medical Sciences, Zarqa College, Al-Balqa Applied University, Zarqa - Jordan.ORCID https://orcid.org/0000-0002-5581-8833
Tareq Nayef AlRamadnehDepartment of Medical Laboratory Sciences, Faculty of Allied Medical Sciences, Al-Ahliyya Amman University, Amman - Jordan.
Moath AlqaralehDepartment of Medical Laboratory Sciences, Faculty of Allied Medical Sciences, Al-Balqa Applied University, Al-Salt - Jordan.
Alqassem H AbuarqoubDepartment of Medical Laboratory Sciences, Faculty of Allied Medical Sciences, Al-Ahliyya Amman University, Amman - Jordan.
Ahmad Al TibiBiolab Diagnostic Laboratories, Amman - Jordan.
Mu'ad Al-Zu'abeDepartment of Allied Medical Sciences, Zarqa College, Al-Balqa Applied University, Zarqa - Jordan.
Sara AbazaDepartment of Allied Medical Sciences, Zarqa College, Al-Balqa Applied University, Zarqa - Jordan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Traumatic brain injury (TBI) is linked to poor progression and a high mortality rate. It is classified and evaluated using the standard Glasgow Coma Scale (GCS). In addition, serum biomarkers, such as vascular endothelial growth factor (VEGF), procalcitonin (PCT), and tumor necrosis factor-alpha (TNF-α), may facilitate accurate TBI severity evaluation, thereby assisting in its prognosis and clinical outcome. Methods: This study included 20 patients with TBI aged ≥18 years who were admitted within 12 h of injury to the intensive care unit (ICU). Serum samples for assessing VEGF, TNF-α, and PCT concentrations were acquired at admission 0 h, 24 h, and 72 h and analyzed by ELISA. Results: Serum concentrations of VEGF, TNF-α, and PCT ( Conclusion: Serum PCT concentrations can be utilized to track the progression of TBI because of a continuous increase in its concentration with time.

Indexed as

ProcalcitoninPrognosisTraumatic brain injuryTumor necrosis factor-alphaVascular endothelial growth factor

Identifiers

PMID42179683
PMCPMC13192403

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.