ArticleACS omega2026
A Dual-Functioning Embolic Microsphere Platform for Combined Antiangiogenic and Anti-Inflammatory Therapy for Rheumatoid Arthritis.
Article in ACS omega, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
7 authors.
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Abstract
Rheumatoid arthritis (RA) is a chronic autoimmune disorder characterized by progressive synovial inflammation and joint destruction, with knee involvement prevalent in approximately 90% of patients. Current local therapies, such as intra-articular injections, often yield transient benefits owing to rapid drug clearance and failure to target pathological neovascularization, highlighting the need for innovative approaches. In this study, we developed a dual-functioning embolic microsphere platform, ETN-GMA/MS, which combines genicular artery embolization with the sustained local delivery of etanercept (ETN), a tumor necrosis factor-α inhibitor, and aimed to assess its therapeutic efficacy in suppressing synovial inflammation and aberrant angiogenesis in an
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