Evidence map›Paper›PMID 42179617›Full record

ArticleACS omega2026

Development of a 17-DMAG-Loaded Carboxymethylcellulose Gel for

Kercia Pinheiro Cruz, Mariana Rolemberg Gueudeville Silveira, Igor Rolemberg Gueudeville Silveira, Jade Liz Ferreira Mendes Souza, Marina Faillace De Amorim, Alan Gualberto De Souza De Freitas De Pinho, Ana Luiza de Jesus Cordeiro, Izabella Gouveia Oliveira, Isadora Dos Santos Lima, Claudia Ida Brodskyn and 7 more

Abstract read
In one paragraph

Article in ACS omega, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Kercia Pinheiro CruzLaboratory of Host-Parasite Interaction and Epidemiology, Gonçalo Moniz Institute, Fiocruz-Bahia, Rua Waldemar Falcão, 121, bairro Candeal, Salvador, BA CEP 40296-710, Brazil.
Mariana Rolemberg Gueudeville SilveiraLaboratory of Host-Parasite Interaction and Epidemiology, Gonçalo Moniz Institute, Fiocruz-Bahia, Rua Waldemar Falcão, 121, bairro Candeal, Salvador, BA CEP 40296-710, Brazil.
Igor Rolemberg Gueudeville SilveiraLaboratory of Host-Parasite Interaction and Epidemiology, Gonçalo Moniz Institute, Fiocruz-Bahia, Rua Waldemar Falcão, 121, bairro Candeal, Salvador, BA CEP 40296-710, Brazil.
Jade Liz Ferreira Mendes SouzaLaboratory of Host-Parasite Interaction and Epidemiology, Gonçalo Moniz Institute, Fiocruz-Bahia, Rua Waldemar Falcão, 121, bairro Candeal, Salvador, BA CEP 40296-710, Brazil.ORCID https://orcid.org/0009-0005-0973-7337
Marina Faillace De AmorimLaboratory of Host-Parasite Interaction and Epidemiology, Gonçalo Moniz Institute, Fiocruz-Bahia, Rua Waldemar Falcão, 121, bairro Candeal, Salvador, BA CEP 40296-710, Brazil.
Alan Gualberto De Souza De Freitas De PinhoLaboratory of Host-Parasite Interaction and Epidemiology, Gonçalo Moniz Institute, Fiocruz-Bahia, Rua Waldemar Falcão, 121, bairro Candeal, Salvador, BA CEP 40296-710, Brazil.
Ana Luiza de Jesus CordeiroLaboratory of Host-Parasite Interaction and Epidemiology, Gonçalo Moniz Institute, Fiocruz-Bahia, Rua Waldemar Falcão, 121, bairro Candeal, Salvador, BA CEP 40296-710, Brazil.
Izabella Gouveia OliveiraLaboratory of Host-Parasite Interaction and Epidemiology, Gonçalo Moniz Institute, Fiocruz-Bahia, Rua Waldemar Falcão, 121, bairro Candeal, Salvador, BA CEP 40296-710, Brazil.
Isadora Dos Santos LimaLaboratory of Host-Parasite Interaction and Epidemiology, Gonçalo Moniz Institute, Fiocruz-Bahia, Rua Waldemar Falcão, 121, bairro Candeal, Salvador, BA CEP 40296-710, Brazil.
Claudia Ida BrodskynLaboratory of Host-Parasite Interaction and Epidemiology, Gonçalo Moniz Institute, Fiocruz-Bahia, Rua Waldemar Falcão, 121, bairro Candeal, Salvador, BA CEP 40296-710, Brazil.
Juliana Perrone Bezerra de MenezesLaboratory of Host-Parasite Interaction and Epidemiology, Gonçalo Moniz Institute, Fiocruz-Bahia, Rua Waldemar Falcão, 121, bairro Candeal, Salvador, BA CEP 40296-710, Brazil.
Deborah Bittencourt MotteLaboratory of Host-Parasite Interaction and Epidemiology, Gonçalo Moniz Institute, Fiocruz-Bahia, Rua Waldemar Falcão, 121, bairro Candeal, Salvador, BA CEP 40296-710, Brazil.
Henrique Rodrigues MarcelinoDepartment of Medicines, College of Pharmacy, Federal University of Bahia, Salvador 40170-115, Bahia, Brazil.ORCID https://orcid.org/0000-0002-3625-7786
Fabio Rocha FormigaAggeu Magalhães Institute, Oswaldo Cruz Foundation (FIOCRUZ), Recife 50670-420, Pernambuco, Brazil.ORCID https://orcid.org/0000-0003-1553-0533
Washington Luis Conrado Dos SantosLaboratory of Structural and Molecular Pathology, Gonçalo Moniz Institute, Oswaldo Cruz Foundation (FIOCRUZ), Rua Waldemar Falcão, 121, bairro Candeal, Salvador - BA, CEP: 40296-710, Brazil.
Thamires Quadros FroesLaboratory of Host-Parasite Interaction and Epidemiology, Gonçalo Moniz Institute, Fiocruz-Bahia, Rua Waldemar Falcão, 121, bairro Candeal, Salvador, BA CEP 40296-710, Brazil.ORCID https://orcid.org/0000-0001-7951-7560
Patricia Sampaio Tavares VerasLaboratory of Host-Parasite Interaction and Epidemiology, Gonçalo Moniz Institute, Fiocruz-Bahia, Rua Waldemar Falcão, 121, bairro Candeal, Salvador, BA CEP 40296-710, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cutaneous leishmaniasis (CL) is a neglected tropical disease for which safer and more effective therapeutic options are urgently needed. Heat shock protein 90 (Hsp90) inhibitors have emerged as promising antileishmanial agents. Among geldanamycin derivatives, 17-dimethylaminoethylamino-17-demethoxygeldanamycin (17-DMAG) has previously demonstrated potent activity against

Identifiers

PMID42179617
PMCPMC13191516

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.