ArticleChemistry (Weinheim an der Bergstrasse, Germany)2026
Pd-Catalyzed Hydroalkoxycarbonylation and Hydroxycarbonylation: DFT Mapping of Catalyst-Substrate Landscape for Product Selectivity.
Article in Chemistry (Weinheim an der Bergstrasse, Germany), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
Hydroalkoxycarbonylation of internal alkenes offers a promising strategy for constructing bridged bicyclic lactones. In this work, density functional theory (DFT) calculations were employed to elucidate the detailed reaction mechanisms leading to both bridged bicyclic lactones and unsaturated carboxylic acids in Pd-catalyzed transformations of cyclopent-3-en-1-ol derivatives. The study examines how variations in catalyst and substrate structure influence product selectivity. DFT calculations reveal that, for the formation of unsaturated carboxylic acids, the presence of a β-hydrogen is crucial. In contrast, the pathway to bicyclic lactones diverges depending on the palladium (Pd) source. With Pd(TFA)
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.