Evidence map›Paper›PMID 42178949›Full record

ArticleJMIR research protocols2026

A Compassion-Focused Online Single-Session Intervention to Reduce Academic Stress in University Students: Protocol for a Randomized Controlled Trial.

Clara Wehlage, Sofija Zivanovic, Helen Koechlin, Nathalie Sarah Schicktanz, Olivia Bolt, Dorothée Bentz

Abstract readClinical Trial Protocol
In one paragraph

Article in JMIR research protocols, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Clara WehlageClinical Psychology and Translational Psychotherapy Research, Faculty of Psychology, University of Basel, Missionsstrasse 62A, Basel, Basel-City, 4055, Switzerland, 41 612070229.ORCID 0009-0006-1043-9190
Sofija ZivanovicClinical Psychology and Translational Psychotherapy Research, Faculty of Psychology, University of Basel, Missionsstrasse 62A, Basel, Basel-City, 4055, Switzerland, 41 612070229.ORCID 0009-0001-3267-8006
Helen KoechlinDepartment of Psychosomatics and Psychiatry, University Children's Hospital, University of Zurich, Zurich, Switzerland.ORCID 0000-0001-6680-8027
Nathalie Sarah SchicktanzCognitive Neuroscience, Department of Biomedicine, University of Basel, Basel, Basel-City, Switzerland.ORCID 0000-0002-6049-6306
Olivia BoltClinical Psychology and Translational Psychotherapy Research, Faculty of Psychology, University of Basel, Missionsstrasse 62A, Basel, Basel-City, 4055, Switzerland, 41 612070229.ORCID 0009-0006-9968-8686
Dorothée BentzClinical Psychology and Translational Psychotherapy Research, Faculty of Psychology, University of Basel, Missionsstrasse 62A, Basel, Basel-City, 4055, Switzerland, 41 612070229.ORCID 0000-0003-0291-2356

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Among university students, the experience of academic stress is associated with symptoms of anxiety and depression. Single-session interventions (SSIs) are structured and accessible self-guided interventions, often delivered digitally, that integrate elements of empirically supported treatments. Compassion-Focused Therapy (CFT) has been shown to be beneficial in alleviating stress, anxiety, and depression. However, the effectiveness of CFT (1) in the academic context, and (2) when delivered in brief digital formats, has not yet been tested. Objective: This study aims to evaluate the effectiveness of a compassion-focused online SSI for reducing stress among university students. Methods: University students aged 18-65 years that indicate at least mild stress (a score >7 on the stress scale of the Depression Anxiety Stress Scale-21 [DASS-21]) will be recruited from German-speaking Switzerland. The target sample size is 156 participants randomly assigned to either the intervention or the waitlist control group. The 45-minute intervention follows the typical SSI structure and combines psychoeducation on academic stress, core CFT principles, guided breathing, compassion imagery exercises, and includes an action plan. Assessments will be conducted at baseline, 24 hours after the intervention, and at the 1-week follow-up. The primary outcome is the change in stress between baseline and 1-week follow-up, measured with the stress scale of the DASS-21. Secondary outcomes include depressive symptoms and anxiety measured with the depression and anxiety scales of the DASS-21 between baseline and 1-week follow-up. Data will be analyzed using linear (mixed-effects) models. Results: Ethical approval for the study was received in September 2025. Recruitment and data collection started in November 2025; data collection will conclude once 172 participants have been enrolled. As of April 15, 2026, 67 participants have been enrolled. Data analysis is planned for winter 2026, with the primary findings being prepared for publication in the spring of 2027. Conclusions: To our knowledge, this study is the first randomized controlled trial to examine the effects of a compassion-focused online SSI on reducing stress in university students. If the program proves to be effective, it would offer a low-threshold, cost-effective, and scalable mental health intervention for the academic context.

Indexed as

EmpathyStress, PsychologicalStudentsAdolescentAdultDepressionFemaleHumansMaleMiddle AgedRandomized Controlled Trials as TopicSwitzerlandUniversitiesYoung Adultacademic stresscompassion-focused therapyinternet-deliveredsingle-session interventionuniversity students

Identifiers

PMID42178949
PMCPMC13199640

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.