ReviewThe Journal of international medical research2026
Correlation between hyperuricemia and coronary artery calcification.
Review in The Journal of international medical research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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0 citing papers in PubMed.
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This review aims to systematically explore the association between hyperuricemia and the degree of coronary artery calcification. We conducted a narrative review of scientific studies published over the past 5 years that examined the relationship between hyperuricemia and coronary artery calcification. The focus was on synthesizing evidence from epidemiological investigations, mechanistic studies, and clinical trials. Recent evidence confirms a significant epidemiological association between elevated serum uric acid levels and the prevalence and progression of coronary artery calcification. Mechanistic studies have identified multiple pathways through which uric acid promotes calcification, including inducing oxidative stress, causing endothelial dysfunction, triggering the phenotypic transformation of vascular smooth muscle cells into osteoblast-like cells, and fostering chronic inflammation. Hyperuricemia contributes to the development and progression of coronary artery calcification through a complex interplay of pathological mechanisms.
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Registered trials
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