Evidence map›Paper›PMID 42178540›Full record

ArticleBMC pregnancy and childbirth2026

Placental and umbilical cord morphometry in preeclampsia and their association with neonatal outcomes: a preliminary study in Ghana.

Rita Agyei Boakye, Nancy Darkoa Darko, Atta Kusi Appiah, Chrissie Stansie Abaidoo, Juliet Robertson, Frank Enoch Gyamfi, Francis Kofi Sarkodie, Ronald Awoonor-Williams, Emmanuel Ansah Owusu

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Article in BMC pregnancy and childbirth, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

9 authors.

Rita Agyei BoakyeDepartment of Anatomy, School of Medical Sciences, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana. ahenewaagy@gmail.com.
Nancy Darkoa DarkoDepartment of Anatomy, School of Medical Sciences, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana.
Atta Kusi AppiahDepartment of Anatomy, School of Medical Sciences, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana.
Chrissie Stansie AbaidooDepartment of Anatomy, School of Medical Sciences, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana.
Juliet RobertsonDepartment of Anatomy, School of Medical Sciences, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana.
Frank Enoch GyamfiDirectorate of Surgery, Komfo Anokye Teaching Hospital, Kumasi, Ghana.
Francis Kofi SarkodieDepartment of Anatomy, School of Medical Sciences, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana.
Ronald Awoonor-WilliamsDepartment of Anatomy, School of Medical Sciences, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana.
Emmanuel Ansah OwusuDepartment of Anatomy, School of Medical Sciences, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe placenta and umbilical cord play a crucial role in fetal growth, development, and neonatal survival. Although extensively studied in developed countries, quantitative data on placental and umbilical cord morphology in preeclampsia are scarce in Ghana. This study aimed to assess the gross morphometry of preeclamptic placentae and umbilical cords and their relationship with neonatal indices.

methodA cross-sectional study was conducted on 152 freshly delivered placentae (100 normotensive; 52 preeclamptic) at the Holy Family Hospital, Berekum, Ghana. Maternal data collected included age, parity, blood pressure, and occupation. Standard anthropometric techniques were used for placental and umbilical cord measurements after they were fixed with 10% neutral buffered formalin. Statistical analyses included t-test, Chi-square, and Spearman correlation, with significance set at p < 0.05.

resultsPlacental and umbilical cord indices differed significantly between preeclamptic and normotensive groups, except for cord length. Moderate to strong correlations were observed between placental and cord indices and neonatal outcomes, but not with neonatal length. Placentae were more often oval, and cords were eccentrically inserted in preeclamptic births compared to normotensive births.

conclusionsPreeclampsia is associated with altered placental and umbilical cord morphology and reduced neonatal growth indices. These findings provide baseline data to support multidisciplinary strategies for improved management and pregnancy outcomes in Ghana.

Indexed as

PlacentaPre-EclampsiaUmbilical CordAdultBirth WeightCross-Sectional StudiesFemaleGhanaHumansInfant, NewbornPregnancyPregnancy OutcomeYoung AdultGhanaMorphometricNeonatal indicisNormotensivePlacentaPreeclampsiaUmbilical cord

Identifiers

PMID42178540
PMCPMC13455443

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