Evidence map›Paper›PMID 42178528›Full record

ArticleBMC cancer2026

PAX1 methylation for triage of HR-HPV-positive women: a comparative analysis with cytology and HPV16/18 genotyping.

Zhengjiao Tong, Saiping Mao, Hong Tao, Peng Gan, Hongtao Li, Xiaozhu Pei, Xing Fan

Abstract readComparative Study
In one paragraph

Article in BMC cancer, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Zhengjiao Tong *Department of Obstetrics & Gynecology, Changsha Hospital for Maternal & Child Health Care Affiliated to Hunan Normal University, Changsha, 410007, China.ORCID http://orcid.org/0009-0005-9988-4022
Saiping Mao *Department of Obstetrics & Gynecology, Changsha Hospital for Maternal & Child Health Care Affiliated to Hunan Normal University, Changsha, 410007, China.ORCID http://orcid.org/0009-0003-2758-7198
Hong TaoDepartment of Medicine, Hunan Hoomya Gene Technology Co., Ltd., Changsha, 410205, China.ORCID http://orcid.org/0000-0003-0019-3861
Peng GanDepartment of Medicine, Hunan Hoomya Gene Technology Co., Ltd., Changsha, 410205, China.ORCID http://orcid.org/0009-0003-7044-0650
Hongtao LiDepartment of Medicine, Hunan Hoomya Gene Technology Co., Ltd., Changsha, 410205, China.ORCID http://orcid.org/0009-0005-2444-8453
Xiaozhu PeiDepartment of Medicine, Hunan Hoomya Gene Technology Co., Ltd., Changsha, 410205, China. peixiaozhu@163.com.ORCID http://orcid.org/0009-0007-0105-2338
Xing FanDepartment of Obstetrics & Gynecology, Changsha Hospital for Maternal & Child Health Care Affiliated to Hunan Normal University, Changsha, 410007, China. fx13327216229@163.com.ORCID http://orcid.org/0009-0004-5639-0463

Funding

Research Project of the Department of Science and Technology of Changsha kh2302012
6 · The paper itself

Abstract

objectiveTo evaluate PAX1 hypermethylation (PAX1

methodsThis prospective, diagnostic accuracy study enrolled 1,461 h-HPV-positive women. All underwent colposcopy and biopsy. Triage strategies (PAX1

resultsPAX1

conclusionThe PAX1

trial registrationNot available.

Indexed as

DNA MethylationHuman papillomavirus 16Human papillomavirus 18Paired Box Transcription FactorsPapillomavirus InfectionsUterine Cervical DysplasiaUterine Cervical NeoplasmsAdultColposcopyCytodiagnosisFemaleGenotypeHumansMiddle AgedProspective StudiesSensitivity and SpecificityPaired Box Transcription FactorsPAX1 transcription factorCervical cancerColposcopyHigh-risk human papillomavirusPAX1 methylationTriage strategy

Identifiers

PMID42178528
PMCPMC13386616

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.