ArticleHemodialysis international. International Symposium on Home Hemodialysis2026
Intima-Media Thickness Progression Rate and Primary Unassisted Patency Failure in Arteriovenous Fistulas: A Prospective Cohort Study.
Article in Hemodialysis international. International Symposium on Home Hemodialysis, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundFailure of autogenous arteriovenous fistulas (AV fistulas) due to venous neointimal hyperplasia is a major clinical challenge. Whether the rate of progression in venous intima-media thickness predicts primary unassisted patency failure remains unknown.
methodsIn this prospective cohort study, we performed a 6-month landmark analysis to minimize immortal time bias among patients with newly created AV fistulas. Intima-media thickness was measured serially by ultrasound. We calculated the early progression rate (0-6 months) as the primary predictor and the 0-12 month rate as a sensitivity analysis. Cox proportional hazards models were used to assess the association between the early progression rate and subsequent primary unassisted patency failure.
resultsThe analysis included 129 patients who were event-free at the 6-month landmark. Over a median follow-up of 13.2 months after the landmark, 35 patients (27.1%) experienced primary unassisted patency failure. Faster early intima-media thickness progression was a strong independent predictor of failure (adjusted hazard ratio [HR] 1.63 per 0.05 mm/year increase; 95% CI 1.41-1.88; p < 0.001), together with baseline intima-media thickness and diabetes. Adding the early progression rate to a model containing clinical and baseline ultrasound variables significantly improved discrimination (C-index increased from 0.69 to 0.76, p = 0.002) and risk reclassification (net reclassification improvement = 0.21, p = 0.008).
conclusionsEarly venous intima-media thickness progression rate is a powerful independent predictor of subsequent AV fistula failure and adds substantial prognostic value beyond standard clinical and ultrasound factors. Serial ultrasound monitoring of this parameter may support the development of risk-adapted surveillance strategies to prolong AV fistula survival.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.