ArticleClinical oral investigations2026
Long-Term Changes Following Orthopedic Mandibular Advancement Therapy in Pediatric Obstructive Sleep Apnea: a 7-Year Follow-up Study.
Article in Clinical oral investigations, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
STUDY
objectivesTo evaluate long-term changes in craniofacial morphology, upper airway dimensions, and sleep-related parameters following monoblock mandibular advancement therapy in children with obstructive sleep apnea (OSA).
methodsThis longitudinal follow-up study included 13 children (mean age 10.97 ± 1.51 years) with OSA and mandibular retrognathia treated with a monoblock appliance. The mean duration of active treatment was 8.06 ± 1.29 months. Assessments were conducted at baseline (T1), post-treatment (T2), and 7 years after treatment (T3), including lateral cephalometric radiographs, polysomnography (PSG), and Pittsburgh Sleep Quality Index (PSQI) scores. Pharyngeal airway changes were analyzed using a standardized cephalometric protocol across 11 sagittal reference planes. Repeated measures ANOVA and nonparametric equivalents were applied for longitudinal comparisons.
resultsIncreases in oropharyngeal and hypopharyngeal airway dimensions (S6-S10; referring to standardized sagittal measurement planes) observed after treatment were generally maintained over time. Skeletal parameters showed relative stability at follow-up. Although Apnea-Hypopnea Index (AHI) decreased significantly after treatment, an increase was noted at T3. The percentage of REM (Rapid Eye Movement) sleep showed no significant change between T1 and T2, whereas a statistically significant increase was observed at T3. PSQI scores improved initially and did not show significant long-term deterioration.
conclusionsThis study provides long-term follow-up data on craniofacial, airway, and sleep-related changes in children with OSA treated with a monoblock appliance. Although partial recurrence of AHI was observed during adolescence, airway dimensions and skeletal parameters demonstrated relative stability over time. These findings suggest that structural adaptations may be maintained, while functional outcomes may vary during growth. Given the multifactorial nature of pediatric OSA, these results should be interpreted cautiously and warrant further investigation in larger longitudinal studies.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.