Evidence map›Paper›PMID 42178221›Full record

ArticleInternational journal for quality in health care : journal of the International Society for Quality in Health Care2026

Prevalence of chemical restraint use in hospital care: a consensus and cross-sectional study.

Jodie B Hillen, Martin L Canning, Nagham J Ailabouni, Hunter Alker, Grace Hart, Dicky Soen, Christopher R Freeman

Abstract read
In one paragraph

Article in International journal for quality in health care : journal of the International Society for Quality in Health Care, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Jodie B HillenSafe and Effective Medication Research Collaborative, Faculty of Health, Medicine and Behavioural Sciences, The University of Queensland, St Lucia, QLD 4067, Australia.ORCID 0000-0001-9269-9397
Martin L CanningMetro North Health, Queensland Health, Herston, QLD 4006, Australia.ORCID 0000-0002-6216-8728
Nagham J AilabouniSafe and Effective Medication Research Collaborative, Faculty of Health, Medicine and Behavioural Sciences, The University of Queensland, St Lucia, QLD 4067, Australia.
Hunter AlkerSchool of Pharmacy and Pharmaceutical Sciences, Faculty of Health, Medicine and Behavioural Sciences, The University of Queensland, Dutton Park, QLD 4102, Australia.
Grace HartSchool of Pharmacy and Pharmaceutical Sciences, Faculty of Health, Medicine and Behavioural Sciences, The University of Queensland, Dutton Park, QLD 4102, Australia.
Dicky SoenSchool of Pharmacy and Pharmaceutical Sciences, Faculty of Health, Medicine and Behavioural Sciences, The University of Queensland, Dutton Park, QLD 4102, Australia.
Christopher R FreemanSafe and Effective Medication Research Collaborative, Faculty of Health, Medicine and Behavioural Sciences, The University of Queensland, St Lucia, QLD 4067, Australia.ORCID 0000-0001-6429-0316

Funding

National Health and Medical Research Council (NHMRC) GNT2025939
6 · The paper itself

Abstract

backgroundRestrictive practices are interventions that limit the rights or freedom of movement of a care recipient. Using medicines to manage behaviours that pose a threat to the patient or others is referred to as chemical restraint. Guidance in Australia for monitoring chemical restraint has largely focused on the aged care and disability sectors. In contrast, far less is known about chemical restraint use in the hospital inpatient setting. This study aims to reach a health service-wide consensus on a chemical restraint definition and a list of medicines used for inpatient care. It also aims to determine the prevalence of chemical restraint use across a large health network.

methodsA modified-Delphi consensus and cross-sectional period prevalence study was undertaken across a large health service in Australia. A multidisciplinary clinical reference group participated in three survey rounds to determine a definition and list of medicines. Period prevalence (%) was determined using inpatient medical notes, and differences between clinical speciality prescriptions and administration were determined by odds ratio (P < .05).

resultsThe Australian Commission on Safety and Quality in Healthcare definition was adopted, and any prescription of an antipsychotic, sedative/hypnotic, ketamine, or propofol was assessed. There were 16.73% (95% CI 14.4% to 19.1%) of patients prescribed and 10.03% (95% CI 7.97% to 12.09%) administered a medicine for chemical restraint. Chemical restraint was prevalent across a range of clinical specialties, with mental health patients 17 times more likely to be exposed ([OR] 17.18, 95% CI 8.74-33.77, P < .001). Olanzapine was the most commonly prescribed medicine (69, 29.11%) with 79.75% (189) of all medicines prescribed pro re nata. Consent was documented for four (5.63%) patients.

conclusionChemical restraint is prescribed across a range of hospital clinical specialties with low rates of documented consent. Adopting a standardized approach could improve existing hospital safety and quality policy and practices.

Indexed as

Hypnotics and SedativesAdultAgedAntipsychotic AgentsAustraliaConsensusCross-Sectional StudiesDelphi TechniqueFemaleHumansMaleMiddle AgedPrevalenceAntipsychotic AgentsHypnotics and Sedativesacute careantipsychotic agentschemical restrainthospitalshypnotics and sedativesmedication therapy management

Identifiers

PMID42178221
PMCPMC13253151

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.