Evidence map›Paper›PMID 42177750›Full record

ArticleClinical pharmacology and therapeutics2026

Cutaneous Adverse Drug Reactions Associated With BRAF and MEK Inhibitors: A Real-World Analysis of WHO Pharmacovigilance Data.

Natalia Sauer, Piotr Giedziun, Jacek Calik, Anna Wiela-Hojeńska

Abstract read
In one paragraph

Article in Clinical pharmacology and therapeutics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Natalia SauerDepartment of Clinical Pharmacology, Faculty of Pharmacy, Wroclaw Medical University, Wroclaw, Poland.ORCID 0000-0002-1898-3952
Piotr GiedziunDepartment of Artificial Intelligence, Wroclaw University of Science and Technology, Wroclaw, Poland.
Jacek CalikOld Town Clinic, Wrocław, Poland.ORCID 0000-0002-4492-8551
Anna Wiela-HojeńskaDepartment of Clinical Pharmacology, Faculty of Pharmacy, Wroclaw Medical University, Wroclaw, Poland.ORCID 0000-0003-3813-2300

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BRAF inhibitors and MEK inhibitors (MEKi) have reshaped the treatment of BRAF

Indexed as

Antineoplastic AgentsDrug EruptionsProtein Kinase InhibitorsProto-Oncogene Proteins B-rafAdultAdverse Drug Reaction Reporting SystemsAgedDatabases, FactualFemaleHumansMaleMiddle AgedPharmacovigilanceRetrospective StudiesAntineoplastic AgentsBRAF protein, humanProtein Kinase InhibitorsProto-Oncogene Proteins B-raf

Identifiers

PMID42177750
PMCPMC13264462

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.