Evidence map›Paper›PMID 42177667›Full record

ArticleJACC. Case reports2026

Descending Aorta Perforation During Transseptal Puncture for Left Atrial Appendage Closure.

Tommaso Bini, Stefania Quintiliani, Vladimir Makaloski, Roberto Galea, Lorenz Räber, Nicolas Brugger

Abstract readCase Reports
In one paragraph

Article in JACC. Case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Tommaso BiniDepartment of Cardiology, Bern University Hospital, University of Bern, Bern, Switzerland.
Stefania QuintilianiDepartment of Cardiology, Bern University Hospital, University of Bern, Bern, Switzerland.
Vladimir MakaloskiDepartment of Vascular Surgery, Bern University Hospital, University of Bern, Bern, Switzerland.
Roberto GaleaDepartment of Cardiology, Bern University Hospital, University of Bern, Bern, Switzerland.
Lorenz RäberDepartment of Cardiology, Bern University Hospital, University of Bern, Bern, Switzerland.
Nicolas BruggerDepartment of Cardiology, Bern University Hospital, University of Bern, Bern, Switzerland. Electronic address: nicolas.brugger@insel.ch.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAortic root injury during transseptal puncture (TSP) is a rare but well-recognized complication. However, injury to the descending aorta has not previously been described in this context. CASE SUMMARY: A 57-year-old woman underwent left atrial appendage closure. During TSP using the VersaCross Connect radiofrequency-powered system and a 15-F steerable sheath, an unrecognized perforation of the descending aorta occurred. Despite repeated transthoracic echocardiograms showing no pericardial effusion and initial hemodynamic stability, she subsequently developed a mediastinal hematoma and bilateral pleural effusion. Management required an emergency percutaneous thoracic endovascular aortic repair, followed by surgical evacuation of the hematoma. DISCUSSION: Excessive tenting during radiofrequency-powered TSP, related to interatrial septum aneurysm, resulted in injury to the descending aorta with life-threatening consequences. TAKE-HOME MESSAGE: Radiofrequency-powered systems for TSP have enhanced tissue penetration capability and should therefore be used with caution, particularly in the presence of an interatrial septum aneurysm and atypical echocardiographic windows.

Indexed as

anticoagulationatrial fibrillationcomplicationcomputed tomographyhemorrhage

Identifiers

PMID42177667
PMCPMC13326227

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.