Evidence map›Paper›PMID 42177649›Full record

ArticleEnvironmental science & technology2026

PFAS Mixture Composition and Internal Exposure Profiles Shape Biological Responses under Field-Realistic Exposure.

Alan M Vajda, Jill A Jenkins, David W Bertolatus, Denis R LeBlanc, Christopher J Martyniuk, Zachary R Hopkins, Andrea K Tokranov, Abigail R Dethloff, Joseph C Tucker, Rainer Lohmann and 1 more

Abstract read
In one paragraph

Article in Environmental science & technology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Alan M VajdaUniversity of Colorado Denver, P.O. Box 173364, Denver, Colorado 80217-3364, United States.ORCID 0000-0001-8309-6025
Jill A JenkinsU.S. Geological Survey, Wetland and Aquatic Research Center, Lafayette, Louisiana 70506, United States.ORCID 0000-0002-5087-0894
David W BertolatusAdams State University, Alamosa, Colorado 81101, United States.
Denis R LeBlancU.S. Geological Survey, New England Water Science Center, Northborough, Massachusetts 01532, United States.ORCID 0000-0002-4646-2628
Christopher J MartyniukUniversity of Florida Genetics Institute, College of Veterinary Medicine, Gainesville, Florida 32610, United States.
Zachary R HopkinsU.S. Geological Survey, Eastern Ecological Science Center, Kearneysville, West Virginia 25430, United States.
Andrea K TokranovU.S. Geological Survey, New England Water Science Center, Northborough, Massachusetts 01532, United States.ORCID 0000-0003-4811-8641
Abigail R DethloffUniversity of Florida Genetics Institute, College of Veterinary Medicine, Gainesville, Florida 32610, United States.
Joseph C TuckerUniversity of Colorado Denver, P.O. Box 173364, Denver, Colorado 80217-3364, United States.
Rainer LohmannGraduate School of Oceanography, University of Rhode Island, Narragansett, Rhode Island 02882, United States.ORCID 0000-0001-8796-3229
Larry B BarberU.S. Geological Survey, Boulder, Colorado 80303, United States.ORCID 0000-0002-0561-0831

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Per- and polyfluoroalkyl substances (PFAS) occur as complex mixtures, yet mixture-dependent biological effects under environmentally realistic exposure conditions remain poorly understood. We conducted multiyear (2018, 2019, 2021) continuous-flow, field-based exposures of male fathead minnows (

Indexed as

FluorocarbonsAlkanesulfonic AcidsAnimalsCyprinidaeGroundwaterMaleWater Pollutants, ChemicalAlkanesulfonic AcidsFluorocarbonsperfluorooctane sulfonic acidWater Pollutants, ChemicalAqueous film-forming foams (AFFF)Fathead minnow (Pimephales promelas)Mixture-toxicityPer- and polyfluoroalkyl substances (PFAS)Reproductive biomarkersTranscriptomics

Identifiers

PMID42177649
PMCPMC13262041

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.