Evidence map›Paper›PMID 42177511›Full record

ArticleCancer imaging : the official publication of the International Cancer Imaging Society2026

Assessment of Lean body mass using whole-body low-dose Ct from Pet/Ct to identify cancer Cachexia.

G J O'Keefe, C Senko, S T Lee, S J Gong, S Pillai, R Fogliaro, T Chen, G Ninatti, K Pathmaraj, Z Cao and 4 more

Abstract read
In one paragraph

Article in Cancer imaging : the official publication of the International Cancer Imaging Society, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

G J O'KeefeDepartment of Molecular Imaging and Therapy, Austin Hospital, 145 Studley Road, Heidelberg, Melbourne, VIC, 3084, Australia. graeme.okeefe@austin.org.au.
C SenkoDepartment of Molecular Imaging and Therapy, Austin Hospital, 145 Studley Road, Heidelberg, Melbourne, VIC, 3084, Australia.
S T LeeDepartment of Molecular Imaging and Therapy, Austin Hospital, 145 Studley Road, Heidelberg, Melbourne, VIC, 3084, Australia.
S J GongDepartment of Molecular Imaging and Therapy, Austin Hospital, 145 Studley Road, Heidelberg, Melbourne, VIC, 3084, Australia.
S PillaiDepartment of Molecular Imaging and Therapy, Austin Hospital, 145 Studley Road, Heidelberg, Melbourne, VIC, 3084, Australia.
R FogliaroDepartment of Molecular Imaging and Therapy, Austin Hospital, 145 Studley Road, Heidelberg, Melbourne, VIC, 3084, Australia.
T ChenDepartment of Molecular Imaging and Therapy, Austin Hospital, 145 Studley Road, Heidelberg, Melbourne, VIC, 3084, Australia.
G NinattiDepartment of Molecular Imaging and Therapy, Austin Hospital, 145 Studley Road, Heidelberg, Melbourne, VIC, 3084, Australia.
K PathmarajDepartment of Molecular Imaging and Therapy, Austin Hospital, 145 Studley Road, Heidelberg, Melbourne, VIC, 3084, Australia.
Z CaoOlivia Newton-John Cancer Research Institute, Heidelberg, VIC, 3084, Australia.
I BurvenichOlivia Newton-John Cancer Research Institute, Heidelberg, VIC, 3084, Australia.
L OsellameOlivia Newton-John Cancer Research Institute, Heidelberg, VIC, 3084, Australia.
N HoogenraadOlivia Newton-John Cancer Research Institute, Heidelberg, VIC, 3084, Australia.
A M ScottDepartment of Molecular Imaging and Therapy, Austin Hospital, 145 Studley Road, Heidelberg, Melbourne, VIC, 3084, Australia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionCancer cachexia is a multifactorial syndrome characterised by involuntary weight loss and muscle wasting, commonly seen in patients with advanced malignancies. Lean Body Mass (LBM) assessment is crucial for the early indentification and monitoring of cancer cachexia. Dual-energy X-ray absorptiometry (DEXA) is widely accepted as the gold standard for evaluating body composition. This study aims to develop a method for estimating LBM using whole-body low-dose CT acquired during PET/CT imaging.

methodsA cohort of patients enrolled in a prospective pilot study on cancer cachexia were included in the analysis. All patients underwent both DEXA and [

resultsA total of 32 (13-cachectic, 19-non-cachectic) patients with advanced malignancies were included in the analysis. The TBLMr

conclusionWhole-body low-dose CT obtained from routine [

Indexed as

CachexiaNeoplasmsPositron Emission Tomography Computed TomographyWhole Body ImagingAbsorptiometry, PhotonAdultAgedBody CompositionFemaleFluorodeoxyglucose F18HumansMaleMiddle AgedPilot ProjectsProspective StudiesRadiopharmaceuticalsFluorodeoxyglucose F18RadiopharmaceuticalsCachexiaDEXALean Body Mass (LBM)PET/CT

Identifiers

PMID42177511
PMCPMC13386892

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.