Evidence map›Paper›PMID 42177373›Full record

ArticleAnnals of surgical oncology2026

How to Deal with Median Arcuate Ligament during Pancreaticoduodenectomy? Management Strategies and Impact on Perioperative Outcomes.

Elena Fernandez-de-Sevilla, Maxime K Collard, Raffaele Vincenzo de la Rosa, Sophie Laroche, Iolanda Scoleri, Mehdi Boubaddi, Charles de Ponthaud, Julie Perinel, Julie Leclerc, Ruth Bustamante and 11 more

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Article in Annals of surgical oncology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors.

Elena Fernandez-de-SevillaDepartment of Anaesthesia, Surgery and Interventional Radiology, Gustave Roussy Hospital, University of Paris-Saclay, Villejuif, France. Elena.FERNANDEZ-DE-SEVILLA@gustaveroussy.fr.
Maxime K CollardDepartment of Anaesthesia, Surgery and Interventional Radiology, Gustave Roussy Hospital, University of Paris-Saclay, Villejuif, France.
Raffaele Vincenzo de la RosaDepartment of Hepatobiliary and Digestive Surgery, Rennes University Hospital, Rennes, France.
Sophie LarocheDepartment of Hepatobiliary Surgery and Transplantation, AP-HP Hôpital Paul-Brousse, University of Paris-Saclay, Villejuif, France.
Iolanda ScoleriDepartment of Digestive Surgery and Transplantation, Lille University Hospital, Lille, France.
Mehdi BoubaddiDepartment of Digestive Surgery, Centre Magellan-CHU Bordeaux, Bordeaux, France.
Charles de PonthaudDepartment of Hepato-Biliary and Pancreatic Surgery and Liver Transplantation, AP-HP, Pitié-Salpêtrière Hospital, Paris, France.
Julie PerinelDepartment of Digestive Surgery, Edouard Herriot Hospital, Hospices Civils de Lyon, Lyon, France.
Julie LeclercDepartment of Surgery, Nancy University Hospital Lorraine and Lorraine University, Vandoeuvre-lès Nancy, France.
Ruth BustamanteDepartment of Digestive and Hepato-Pancreatic-Biliary Surgery, Hôpital Henri-Mondor, AP-HP, Paris Est Créteil University, UPEC, Créteil, France.
Pietro AddeoHepato-Pancreato-Biliary Surgery and Liver Transplantation, Pôle des Pathologies Digestives et Hépatiques, Hôpital de Hautepierre-Hôpitaux Universitaires de Strasbourg, Université de Strasbourg, Strasbourg, France.
Rim CherifHepato-Pancreato-Biliary Surgery and Liver Transplantation, Pôle des Pathologies Digestives et Hépatiques, Hôpital de Hautepierre-Hôpitaux Universitaires de Strasbourg, Université de Strasbourg, Strasbourg, France.
Ahmet AyavDepartment of Surgery, Nancy University Hospital Lorraine and Lorraine University, Vandoeuvre-lès Nancy, France.
Mustapha AdhamDepartment of Digestive Surgery, Edouard Herriot Hospital, Hospices Civils de Lyon, Lyon, France.
Sebastien GaujouxDepartment of Hepato-Biliary and Pancreatic Surgery and Liver Transplantation, AP-HP, Pitié-Salpêtrière Hospital, Paris, France.
Christophe LaurentDepartment of Digestive Surgery, Centre Magellan-CHU Bordeaux, Bordeaux, France.
Stephanie TruantDepartment of Digestive Surgery and Transplantation, Lille University Hospital, Lille, France.
Antonio Sa CunhaDepartment of Hepatobiliary Surgery and Transplantation, AP-HP Hôpital Paul-Brousse, University of Paris-Saclay, Villejuif, France.
Laurent SulpiceDepartment of Hepatobiliary and Digestive Surgery, Rennes University Hospital, Rennes, France.
Maximiliano GelliDepartment of Anaesthesia, Surgery and Interventional Radiology, Gustave Roussy Hospital, University of Paris-Saclay, Villejuif, France.
French Association of Hepato-Bilio-Pancreatic Surgery and Liver Transplantation (ACHBPT)

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMedian arcuate ligament (MAL) can cause coeliac trunk (CT) stenosis, which is often asymptomatic but may lead to severe hepatic, splenic, or digestive ischemia following pancreaticoduodenectomy (PD). Optimal diagnosis and management remain debated. The purpose of this study was to evaluate management strategies and perioperative outcomes of patients with MAL undergoing PD. PATIENTS AND

methodsA retrospective multicenter study across ten high-volume French centers included patients diagnosed with MAL (hemodynamically significant or not) who underwent PD between 2005 and 2024. Diagnosis and management strategies and postoperative outcomes were collected.

resultsMAL stenosis was suspected in 1.3% of patients (115/8676), with 59 cases (0.7%) showing hemodynamically significant MAL. MAL stenosis was suspected before surgery in 90% of patients (n = 104). Overall, 8 patients (13.8%) underwent preoperative stenting, 48 patients (82.8%) underwent intraoperative MAL division, and 2 patients (3.4%) underwent primary vascular reconstruction. Seven failures of MAL division (14%) required vascular reconstruction. Overall morbidity (Clavien-Dindo ≥ III) was 25%, pancreatic fistula B-C was 10%, biliary fistula was 6.9%, hemorrhage was 15%, and mortality was 4.3% (n = 5). Ischemic complications were observed in five patients (4.5%), including four hepatic ischemias and one bowel ischemia; two hepatic ischemias were directly related to MAL management. Overall postoperative mortality was 4.3%, with two deaths attributable to MAL-related hepatic ischemia.

conclusionsMAL is rare but clinically impactful in patients undergoing PD. Early recognition and appropriate intraoperative assessment are essential to prevent ischemic complications. When properly identified and managed, MAL does not appear to significantly worsen overall postoperative outcomes. Management should remain individualized, and pancreatic surgeons should be prepared to perform MAL division and vascular reconstruction when indicated.

Indexed as

Celiac artery stenosisMedian arcuate ligamentMulticenter studyPancreaticoduodenectomyPostoperative ischemia

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.