Evidence map›Paper›PMID 42177319›Full record

SynthesisScientific reports2026

Diabetes and the risk of delayed union or non-union of fractures: evidence from a systematic review and meta-analysis.

Jun Li, Zixin Cai, Yi Shen, Jingjing Zhang, Lu Wang, Tang Liu

Abstract readSystematic ReviewMeta-Analysis
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Scientific reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Jun LiDepartment of Orthopedics, The Second Xiangya Hospital, Central South University, Changsha, 410011, Hunan, People's Republic of China.
Zixin CaiDepartment of Metabolism and Endocrinology, The Second Xiangya Hospital, Central South University, Changsha, 410011, Hunan, People's Republic of China.
Yi ShenDepartment of Orthopedics, The Second Xiangya Hospital, Central South University, Changsha, 410011, Hunan, People's Republic of China.
Jingjing ZhangDepartment of Metabolism and Endocrinology, The Second Xiangya Hospital, Central South University, Changsha, 410011, Hunan, People's Republic of China.
Lu WangDepartment of Orthopedics, The Second Xiangya Hospital, Central South University, Changsha, 410011, Hunan, People's Republic of China. wanglu85@csu.edu.cn.
Tang LiuDepartment of Orthopedics, The Second Xiangya Hospital, Central South University, Changsha, 410011, Hunan, People's Republic of China. liutang1204@csu.edu.cn.

Funding

Outstanding Youth Scientist Foundation of Hunan Province 2022JJ10095Scientific Research Program of Furong Laboratory 2023SK2102-2the Hunan Provincial Natural Science Foundation of China 2024JJ7346
6 · The paper itself

Abstract

As the global prevalence of diabetes continues to rise, an increasing number of fracture patients present with metabolic comorbidities, raising concerns regarding their healing outcomes. This systematic review and meta-analysis aimed to provide an updated and comprehensive assessment of the association between diabetes and delayed union or non-union. A comprehensive search of PubMed, Embase, Web of Science, Scopus, CINAHL, and the Cochrane Library was performed from inception to November 2025, following PRISMA guidelines. Two reviewers independently performed study selection, data extraction, and quality assessment. Odds ratios (ORs) with 95% confidence intervals (CIs) were pooled using random-effects models. Heterogeneity was quantified using the I

Indexed as

Diabetes ComplicationsDiabetes MellitusFracture HealingFractures, BoneFractures, UnunitedHumansRisk FactorsDelayed unionDiabetesFracture healingMeta-analysisNon-union

Identifiers

PMID42177319
PMCPMC13416051

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.