Evidence map›Paper›PMID 42176299›Full record

ReviewPest management science2026

Bt agave: why it is time to explore a new biotechnological frontier.

Aline Vitória Corim Marim, Marcelo Falsarella Carazzolle, Gonçalo Amarante Guimarães Pereira, Carolina Rossi De Oliveira

Abstract readReview
In one paragraph

Review in Pest management science, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Aline Vitória Corim MarimGenomics and BioEnergy Laboratory, Biology Institute, University of Campinas, Campinas, Brazil.ORCID https://orcid.org/0009-0005-1272-4051
Marcelo Falsarella CarazzolleGenomics and BioEnergy Laboratory, Biology Institute, University of Campinas, Campinas, Brazil.ORCID https://orcid.org/0000-0002-5474-2830
Gonçalo Amarante Guimarães PereiraGenomics and BioEnergy Laboratory, Biology Institute, University of Campinas, Campinas, Brazil.ORCID https://orcid.org/0000-0003-4140-3482
Carolina Rossi De OliveiraGenomics and BioEnergy Laboratory, Biology Institute, University of Campinas, Campinas, Brazil.ORCID https://orcid.org/0000-0002-3563-4834

Funding

Shell Brasil
6 · The paper itself

Abstract

Drylands cover 41% of Earth's surface and are expanding due to climate change, requiring innovative agricultural strategies for resource efficiency. Agave, a non-conventional drought-tolerant monocot cultivated in Mexico and Brazil, is a sustainable crop with high biomass productivity and low water requirements, supporting industries like biofuels, textiles, and beverages. With high biomass productivity and extremely low water requirements, Agave species are increasingly recognized as one of the most sustainable crops for semi-arid and marginal regions. Despite its environmental resilience, agave cultivation is significantly constrained by insect pests that reduce yield and economic returns. While Bacillus thuringiensis (Bt) Cry proteins have revolutionized pest management in other crops, their application in Agave spp. remains unexplored due to technical barriers in genetic transformation. Here, we argue that the integration of Bt technology into Agave species is both technically feasible and strategically necessary. We discuss recent advances in plant transformation and regeneration that lower historical barriers in monocots and outline how Cry-based resistance could be incorporated into Agave spp. within integrated pest management frameworks. By synthesizing current knowledge and identifying key research priorities, we suggest that Bt-engineered Agave spp. could represent a realistic and timely strategy to enhance pest control, sustainability, and resilience in dryland agricultural systems. © 2026 The Author(s). Pest Management Science published by John Wiley & Sons Ltd on behalf of Society of Chemical Industry.

Indexed as

AgaveBacillus thuringiensisBacillus thuringiensis ToxinsBacterial ProteinsBiotechnologyEndotoxinsHemolysin ProteinsPest Control, BiologicalPlants, Genetically ModifiedAnimalsCrops, AgriculturalBacillus thuringiensis ToxinsBacterial ProteinsEndotoxinsHemolysin Proteinsinsecticidal crystal protein, Bacillus ThuringiensisBt technologyCry proteinsgenetic transformationinsect resistancesemi‐arid agriculture

Identifiers

PMID42176299
PMCPMC13453240

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.