Evidence map›Paper›PMID 42176238›Full record

ReviewJournal of the American Geriatrics Society2026

Clin-STAR Corner: Practice Changing Advances at the Interface of Artificial Intelligence/Machine Learning and Geriatrics.

Tue T Te, Alex A T Bui, William Speier, Constance H Fung

Abstract readReview
In one paragraph

Review in Journal of the American Geriatrics Society, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Tue T TeDepartment of Medicine, David Geffen School of Medicine at University of California, Los Angeles (UCLA), Los Angeles, California, USA.ORCID https://orcid.org/0000-0001-6290-0475
Alex A T BuiMedical & Imaging Informatics Group, Department of Radiological Sciences, David Geffen School of Medicine at University of California, Los Angeles (UCLA), Los Angeles, California, USA.
William SpeierMedical & Imaging Informatics Group, Department of Radiological Sciences, David Geffen School of Medicine at University of California, Los Angeles (UCLA), Los Angeles, California, USA.
Constance H FungDepartment of Medicine, David Geffen School of Medicine at University of California, Los Angeles (UCLA), Los Angeles, California, USA.

Funding

Clin-STAR Coordinating CenterU24AG065204 · NIA · AMERICAN FEDERATION FOR AGING RESEARCH · PI Thomas Michael Gill, Kristine Yaffe · 2019 to 2026
$5.5M
NIA NIH HHS U24 AG065204NIA NIH HHS U24AG065204
6 · The paper itself

Abstract

Artificial intelligence (AI) methods, including machine learning (ML), are transforming healthcare by enabling personalized interventions that integrate multimodal data to support rehabilitation, preventive care, and remote monitoring. Despite their broad potential, older adults remain underrepresented in model development, raising concerns about bias and limited generalizability. As AI/ML adoption expands, it is essential to critically appraise emerging tools to ensure ethical, equitable, person-centered implementation in aging populations and long-term randomized evaluations. A structured MEDLINE search identified randomized controlled trials (RCTs) published between January 2023 and December 2025 that evaluated AI/ML-based interventions in adults ≥ 65 years. Of 31 records identified, 19 underwent abstract screening, seven underwent full-text assessment, and four articles were identified as meeting all criteria for inclusion, which focused on scalability, clinical impact, and methodological rigor. Across postoperative rehabilitation and preventive care, AI/ML interventions demonstrated meaningful clinical benefits. Transformative applications of AI/ML described robotic systems quantifying weight-bearing, algorithm-guided paired rehabilitation interventions, paired exercises in geriatric hip fracture rehabilitation, smartphone platforms delivering continuously personalized exercise programs, and conversational chatbots providing tailored vaccine counseling. The included RCTs show that AI-driven interventions can enhance physical recovery, support psychosocial well-being, and improve uptake of preventive measures compared with conventional approaches. Key considerations for future implementation include digital health literacy, long-term follow-up, and potential bias arising from healthier or more motivated study populations. As evidence grows, geriatric innovation must prioritize safety, ethics, and equitable access to ensure that technological precision enhances, rather than replaces, person-centered care.

Indexed as

Artificial IntelligenceGeriatricsMachine LearningAgedDigital HealthHumansRandomized Controlled Trials as Topicartificial intelligencemachine learningolder adultsrandomized controlled trial

Identifiers

PMID42176238
PMCPMC13589678

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.