ArticleSupportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer2026
Prevalence of preoperative multidimensional frailty and associated factors in middle-aged and older patients with newly diagnosed breast cancer: a cross-sectional study.
Article in Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeFrailty has emerged as a significant predictor of health outcomes. However, multidimensional frailty among middle-aged and older patients with newly diagnosed breast cancer remains understudied. Therefore, this study aims to investigate the prevalence of preoperative multidimensional frailty and its associated factors in this population.
methodsA total of 223 middle-aged and older patients with breast cancer were recruited from the breast surgery ward of a general hospital in China from September 2023 to July 2024. Sociodemographic characteristics, clinical information, biochemical indicators, Tilburg frailty indicator scores, physical activity scale for the elderly scores, and Resnick exercise self-efficacy scale scores were collected from all patients. Chi-square tests and independent samples t-tests were used for univariate analyses, and variables with statistical significance were included in a binary logistic regression to identify factors associated with multidimensional frailty.
resultsThe prevalence of preoperative multidimensional frailty was 36.3% in middle-aged and older patients with newly diagnosed breast cancer. Factors associated with multidimensional frailty included higher exercise self-efficacy (OR = 0.760, p = 0.004), high self-perceived financial distress (OR = 3.996, p = 0.009), living alone (OR = 17.822, p = 0.007), difficulty falling asleep (OR = 2.858, p = 0.005), ≥ 2 comorbidities (OR = 7.995, p = 0.003), low white blood cell count (OR = 5.202, p = 0.011), and overweight or obesity (OR = 0.417, p = 0.014).
conclusionsThe prevalence of preoperative multidimensional frailty is relatively high among middle-aged and older patients with newly diagnosed breast cancer and is associated with exercise self-efficacy, self-perceived financial distress, living arrangement, difficulty falling asleep, number of comorbidities, white blood cell count, and body mass index. Healthcare professionals should assess patient characteristics to identify high-risk patients preoperatively and consider developing targeted interventions to enhance exercise self-efficacy, which may be beneficial for the management of multidimensional frailty and related health outcomes.
Indexed as
Identifiers
42176214What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.