Evidence map›Paper›PMID 42176161›Full record

ArticleOphthalmology and therapy2026

Eye Loss, Orbital Sequelae, and Prosthetic Rehabilitation Following Crowd-Control Kinetic Impact Projectile Injuries: The Largest Civilian Cohort.

Sebastián Córdova, Miguel Ángel Campos, Carmen Torres, Patricio Bustamante, Eric Tapia, Joaquín Varas, Macarena Mesa, Cesar Silva, José Luis Sanhueza

Abstract read
In one paragraph

Article in Ophthalmology and therapy, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Sebastián Córdova *Department of Odontology, Faculty of Odontology, Universidad de Chile, Santiago, Chile.ORCID http://orcid.org/0000-0002-7268-1410
Miguel Ángel Campos *Department of Medical Technology, Faculty of Medicine, Universidad de Chile, Avenida Independencia 1027, comuna de Independencia, 8380453, Santiago, Región Metropolitana, Chile. micamposg@uchile.cl.ORCID http://orcid.org/0000-0002-9215-8248
Carmen TorresDepartment of Ophthalmology, Hospital del Salvador, Santiago, Chile.ORCID http://orcid.org/0009-0003-0148-684X
Patricio BustamanteDepartment of Medical Technology, Faculty of Medicine, Universidad de Chile, Avenida Independencia 1027, comuna de Independencia, 8380453, Santiago, Región Metropolitana, Chile.ORCID http://orcid.org/0000-0003-2144-2572
Eric TapiaDepartment of Medical Technology, Faculty of Medicine, Universidad de Chile, Avenida Independencia 1027, comuna de Independencia, 8380453, Santiago, Región Metropolitana, Chile.ORCID http://orcid.org/0000-0001-8138-1797
Joaquín VarasDepartment of Occupational Therapy, Faculty of Medicine, Universidad de Chile, Santiago, Chile.ORCID http://orcid.org/0000-0001-6845-5261
Macarena MesaDepartment of Medical Technology, Faculty of Medicine, Universidad de Chile, Avenida Independencia 1027, comuna de Independencia, 8380453, Santiago, Región Metropolitana, Chile.ORCID http://orcid.org/0000-0002-9375-8034
Cesar SilvaDepartment of Odontology, Faculty of Odontology, Universidad de Chile, Santiago, Chile.ORCID http://orcid.org/0009-0005-1351-3424
José Luis SanhuezaDepartment of Ophthalmology, Hospital del Salvador, Santiago, Chile.ORCID http://orcid.org/0009-0007-8098-2751

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionDuring the 2019-2020 Chilean social unrest, massive police use of kinetic impact projectiles (KIPs) caused unprecedented severe ocular traumas, initially affecting over 460 individuals. We examined the largest civilian cohort with complete globe loss to characterize orbital/peri-orbital sequelae, analyze projectile-specific injury patterns, and assess factors affecting rehabilitation.

methodsThis retrospective cohort evaluated 57 individuals requiring ocular prostheses at Chile's national referral center (2019-2022). Sociodemographic, clinical, and prosthetic variables were analyzed, encompassing immediate and delayed globe loss (secondary evisceration/phthisis bulbi). Sequelae count associations were assessed via the Kruskal-Wallis test.

resultsKIPs caused 94.7% of irreversible globe losses (pellets 73.7%, a tear-gas projectile 21.1%, blunt trauma 5.3%). A tear-gas projectile was significantly associated with a higher number of concurrent orbital/peri-orbital sequelae per individual (p = 0.002). Prevalent sequelae included palpebral scarring (43.9%), ptosis (26.3%), and orbital fractures (22.8%). Prior conformer shell installation correlated with significantly more sequelae (p = 0.002). This high sequelae burden also correlated with initial prosthetic complications, specifically rotation and intense mucoid discharge (p = 0.011). Overall prosthetic adherence reached 93.0%; notably, 17.5% of users selected non-mimetic (novelty) prostheses.

conclusionsDuring the repression of the 2019-2020 protests, "non-lethal" KIPs proved highly destructive. Beyond the globe loss itself, a tear-gas projectile was significantly associated with a high number of concurrent sequelae, uniquely causing widespread trauma, including maxillofacial fractures. Conversely, pellets-the most frequent KIP-frequently resulted in isolated globe loss but caused specific severe outcomes, including all cases of anophthalmic cavity syndrome and persistent conjunctivitis, alongside most ptosis. Complete globe loss occurred immediately or following a prolonged trajectory. High prosthetic adherence (93.0%) was achieved by offering non-mimetic designs when conventional prostheses were refused, preserving orbital integrity and addressing psychosocial needs. These findings reinforce the global need for multidisciplinary rehabilitation and provide medical evidence to demand the strict regulation of these weapons.

Indexed as

Anophthalmic cavityChileCrowd-control weaponsKinetic impact projectilesOcular traumaOculoplastic and prosthetic rehabilitationOrbital and peri-orbital sequelaeSocial unrest

Identifiers

PMID42176161
PMCPMC13315387

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.