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ArticleObesity surgery2026

Efficacy Analysis of Simultaneous Bariatric Surgery and Radical Thyroidectomy in Patients with Obesity and Low-Risk Papillary Thyroid Cancer: A Pilot Feasibility and Safety Study.

Dehui Wang, Zilong Wu, Yan Liu, Jie Li, Bing Wu, Ruixiang Hu, Cunchuan Wang

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Article in Obesity surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

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7 authors.

Dehui WangDepartment of Gastrointestinal Surgery/Bariatric Surgery Center, The First Affiliated Hospital of Jinan University, Guangzhou, China.
Zilong WuDepartment of Gastrointestinal Surgery/Bariatric Surgery Center, The First Affiliated Hospital of Jinan University, Guangzhou, China.
Yan LiuDepartment of Gastrointestinal Surgery/Bariatric Surgery Center, The First Affiliated Hospital of Jinan University, Guangzhou, China.
Jie LiGuangzhou Municipal and Guangdong Provincial Key Laboratory of Molecular Target & Clinical Pharmacology, School of Pharmaceutical Sciences, Guangzhou Medical University, Guangzhou, China.
Bing WuDepartment of Gastrointestinal Surgery/Bariatric Surgery Center, The Affiliated Hospital of Guizhou Medical University, Guizhou, China.
Ruixiang HuDepartment of Gastrointestinal Surgery/Bariatric Surgery Center, The First Affiliated Hospital of Jinan University, Guangzhou, China. huruixiang123@jnu.edu.cn.
Cunchuan WangDepartment of Gastrointestinal Surgery/Bariatric Surgery Center, The First Affiliated Hospital of Jinan University, Guangzhou, China. twcc@jnu.edu.cn.

Funding

The study was supported by the clinical Frontier Technology Program of the First Affiliated Hospital of Jinan University, China. No. JNU1AF-CFTP-2022-a01202
6 · The paper itself

Abstract

backgroundObesity is an independent risk factor for various chronic diseases and malignancies. The incidence of thyroid cancer is significantly higher in obese populations. Current clinical practice often adopts staged treatment for obesity with thyroid cancer, which presents challenges including cancer management and prolonged recovery. The simultaneous implementation of bariatric surgery and radical thyroidectomy may represent a more efficient therapeutic strategy. This study evaluates the clinical value of this combined approach by comparing clinical data with standalone bariatric surgery, focusing on feasibility, safety, and comparative metabolic and weight loss efficacy.

methodsPatients who underwent laparoscopic bariatric surgery at our center from March 2015 to March 2023 were retrospectively collected. Using propensity score matching method, patients were stratified into two cohorts: the simultaneous group (SS group, n = 24) receiving combined bariatric surgery with radical thyroidectomy, and bariatric surgery group (BS group, n = 72). Surgical outcomes, complications, and 2-year follow-up data were compared.

resultsPreoperative characteristics were comparable (p > 0.05). The SS group had longer operative duration (median 242.50 vs. 104.50 min, p < 0.05) and higher blood loss (35.00 vs. 25.00 mL, p < 0.05) than the BS group, with no significant difference in short-term complications (p > 0.05). At 2 years postoperatively, the SS group reported no hypocalcemia, hypothyroidism, or cancer recurrence. Both groups achieved significant, comparable reductions in weight, body mass index, and metabolic parameters postoperatively.

conclusionsFor patients with obesity complicated by T1-T2N0M0 low-risk papillary thyroid carcinoma, this pilot study demonstrates that simultaneous bariatric surgery and radical thyroidectomy is safe and feasible, without an increased risk of complications. The efficacy of this combined approach in terms of weight loss and metabolic improvement is comparable to that of standalone bariatric surgery, highlighting its clinical application value in centers with relevant combined clinical experience.

Indexed as

Bariatric SurgeryObesityObesity, MorbidThyroid Cancer, PapillaryThyroidectomyThyroid NeoplasmsAdultFeasibility StudiesFemaleHumansMaleMiddle AgedPilot ProjectsPostoperative ComplicationsRetrospective StudiesTreatment OutcomeBariatric surgeryObesityRadical thyroidectomySimultaneous surgeryThyroid cancer

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.