Evidence map›Paper›PMID 42176016›Full record

ArticleEuropean spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society2026

A regression-based equation for postoperative spontaneous correction of the unfused proximal thoracic curve in lenke types 1 and 2 adolescent idiopathic scoliosis.

Masayoshi Iwamae, Shinji Takahashi, Yuki Kinoshita, Minori Kato, Hiromitsu Toyoda, Akinobu Suzuki, Koji Tamai, Yuta Sawada, Yuki Okamura, Yuto Kobayashi and 5 more

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Article in European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

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15 authors.

Masayoshi IwamaeDepartment of Orthopaedic Surgery, Osaka Metropolitan University, Osaka, Japan. m-iwamae@omu.ac.jp.
Shinji TakahashiDepartment of Orthopaedic Surgery, Osaka Metropolitan University, Osaka, Japan. stakahashi@omu.ac.jp.
Yuki KinoshitaDepartment of Orthopaedic Surgery, Osaka Metropolitan University, Osaka, Japan.
Minori KatoDepartment of Orthopaedic Surgery, Osaka Metropolitan University, Osaka, Japan.
Hiromitsu ToyodaDepartment of Orthopaedic Surgery, Osaka Metropolitan University, Osaka, Japan.
Akinobu SuzukiDepartment of Orthopaedic Surgery, Osaka Metropolitan University, Osaka, Japan.
Koji TamaiDepartment of Orthopaedic Surgery, Osaka Metropolitan University, Osaka, Japan.
Yuta SawadaDepartment of Orthopaedic Surgery, Osaka Metropolitan University, Osaka, Japan.
Yuki OkamuraDepartment of Orthopaedic Surgery, Osaka Metropolitan University, Osaka, Japan.
Yuto KobayashiDepartment of Orthopaedic Surgery, Osaka Metropolitan University, Osaka, Japan.
Masato UematsuDepartment of Orthopaedic Surgery, Osaka Metropolitan University, Osaka, Japan.
Hiroshi TaniwakiDepartment of Orthopaedic Surgery, Osaka Metropolitan University, Osaka, Japan.
Masashi TsujinoDepartment of Orthopaedic Surgery, Osaka Metropolitan University, Osaka, Japan.
Hiroaki NakamuraDepartment of Orthopaedic Surgery, Osaka Metropolitan University, Osaka, Japan.
Hidetomi TeraiDepartment of Orthopaedic Surgery, Osaka Metropolitan University, Osaka, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposePostoperative shoulder imbalance (PSI) in adolescent idiopathic scoliosis (AIS) surgery is associated with postoperative T1 tilt. Upper instrumented vertebra (UIV) tilt can be surgically adjusted; however, controlling T1 tilt remains challenging because the postoperative behavior of the unfused proximal thoracic curve (T1-UIV angle) is unpredictable. We aimed to develop and validate a regression-based equation for predicting the final follow-up (FFU) T1-UIV angle in AIS.

methodsIn this retrospective cohort study, we included 97 consecutive patients with AIS (Lenke Types 1 and 2) who underwent surgery. The T1-UIV angle was measured preoperatively, intraoperatively (post-correction), and at FFU. Factors associated with the FFU T1-UIV angle were evaluated using multiple linear regression based on predefined preoperative and surgically adjustable variables, and a regression-based equation was derived. Predictive performance was assessed using a separate internal validation cohort. Predicted T1 tilt, calculated as intraoperative UIV tilt + predicted FFU T1-UIV angle, was evaluated for its association with FFU radiographic shoulder height (RSH).

resultsMultivariate analysis identified the preoperative T1-UIV angle (B = 0.61, p < 0.001) and UIV tilt (B = 0.08, p = 0.030) as independent factors associated with the FFU T1-UIV angle. The regression-based equation was defined as follows: Model 1 = 1.2 + 0.61 × (preoperative T1-UIV angle) + (preoperative UIV tilt / 12). To enhance clinical ease of use, a simplified single-parameter model was also developed: Model 2 = 0.6 × (preoperative T1-UIV angle). Bothmodels demonstrated good internal validity (Model 1: mean absolute error [MAE] = 2.07°, adjusted R² = 0.694; Model 2: MAE = 1.75°, adjustedR² = 0.757), with Model 2 showing comparable predictive performance despite its simplicity. Predicted T1 tilt was significantly associated with FFU RSH (r = 0.517, p < 0.001).

conclusionThese regression-based equations can provide a practical intraoperative reference for UIV tilt adjustment and may help reduce PSI. The simplified Model 2 offers a particularly practical bedside tool.

Indexed as

Adolescent idiopathic scoliosisRadiographic shoulder imbalanceRegression-based equationT1 tiltT1–UIV angleUnfused proximal thoracic

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.