Evidence map›Paper›PMID 42175828›Full record

ArticleAngewandte Chemie (International ed. in English)2026

Long-Acting Dynamic Therapy Using X-Ray Activated Organic Nanoparticles for Afterglow Imaging Guided Deep Tumor Treatment.

Baoli Yin, Peng Liang, Jiahui Sun, Zhe Li, Hengxin Shen, Dehong Hu, Ying Zhou, Shuangyan Huan, Heemin Kang, Cheng Zhang and 3 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Angewandte Chemie (International ed. in English), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Baoli YinState Key Laboratory of Chemo and Biosensing, College of Chemistry and Chemical Engineering, Hunan University, Changsha, China.
Peng LiangState Key Laboratory of Chemo and Biosensing, College of Chemistry and Chemical Engineering, Hunan University, Changsha, China.
Jiahui SunState Key Laboratory of Chemo and Biosensing, College of Chemistry and Chemical Engineering, Hunan University, Changsha, China.
Zhe LiState Key Laboratory of Chemo and Biosensing, College of Chemistry and Chemical Engineering, Hunan University, Changsha, China.
Hengxin ShenState Key Laboratory of Chemo and Biosensing, College of Chemistry and Chemical Engineering, Hunan University, Changsha, China.
Dehong HuResearch Center for Advanced Detection Materials and Medical Imaging Devices, Institute of Biomedical and Health Engineering, Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences, Shenzhen, China.
Ying ZhouState Key Laboratory of Chemo and Biosensing, College of Chemistry and Chemical Engineering, Hunan University, Changsha, China.
Shuangyan HuanState Key Laboratory of Chemo and Biosensing, College of Chemistry and Chemical Engineering, Hunan University, Changsha, China.
Heemin KangDepartment of Materials Science and Engineering, Korea University, Seoul, South Korea.
Cheng ZhangState Key Laboratory of Chemo and Biosensing, College of Chemistry and Chemical Engineering, Hunan University, Changsha, China.ORCID 0009-0005-6570-3772
Zonghai ShengResearch Center for Advanced Detection Materials and Medical Imaging Devices, Institute of Biomedical and Health Engineering, Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences, Shenzhen, China.ORCID 0000-0003-0289-029X
Xiao-Bing ZhangState Key Laboratory of Chemo and Biosensing, College of Chemistry and Chemical Engineering, Hunan University, Changsha, China.
Guosheng SongState Key Laboratory of Chemo and Biosensing, College of Chemistry and Chemical Engineering, Hunan University, Changsha, China.ORCID 0000-0001-5628-6245

Funding

Project of Yuelushan Center for Industrial Innovation 2025YCII0204Shenzhen Medical Research Funds B2302021The Changsha Natural Science Foundation kq2402060The National Key R&D Program of China 2023YFA0915400The National Key R&D Program of China 2024YFA1209404The National Natural Science Foundation of China 22374040The National Natural Science Foundation of China 22404054The National Natural Science Foundation of China 22525402The science and technology innovation Program of Hunan Province 2025RC3101
6 · The paper itself

Abstract

Traditional dynamic therapies, including photodynamic, sonodynamic and chemodynamic therapies, are limited by shallow penetration and lack of sustained effects. X-ray induced dynamic therapy overcomes penetration barriers, yet current inorganic materials raise biosafety concerns, while organic counterparts often show low reactive oxygen species (ROS) yield. To address these limitations, we propose X-ray induced long-acting dynamic therapy, a minimally invasive strategy for deep-tissue tumor treatment. We propose X-ray induced persistent ROS generation and luminescence mechanisms in fused-triple-anthracene nanoparticles (FTA NPs), which generate electrons and FTA

Indexed as

AnthracenesNanoparticlesNeoplasmsAnimalsCell Line, TumorHumansMiceReactive Oxygen SpeciesX-RaysAnthracenesReactive Oxygen Speciesbiomedical engineeringluminescencenanoparticlephotodynamic therapyreactive oxygen species

Identifiers

PMID42175828
PMCPMC13383242

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.