Evidence map›Paper›PMID 42175667›Full record

Trial reportJournal of oral rehabilitation2026

Comparison of the Effects of Different Manual Therapy Techniques on Mandibular Mobility, Cervical Joint Position Sense, Jaw Function and Anxiety Levels in Individuals With Rheumatoid Arthritis and Temporomandibular Disorders: A Randomized Controlled Trial.

Kübra Aktaş, Hakan Polat, Tuba Maden, Burhan Fatih Koçyiğit

Registry-linked trialAbstract readRandomized Controlled TrialComparative Study
In one paragraph

Trial report in Journal of oral rehabilitation, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07171671 (The Effectiveness of Manual Therapy Applications in Individuals With Rheumatoid Arthritis Who Have Temporomandibular Joint Dysfunction), which is not on this map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07171671 nacompletednot on this map

The Effectiveness of Manual Therapy Applications in Individuals With Rheumatoid Arthritis Who Have Temporomandibular Joint Dysfunction

TypeinterventionalSponsorSanko UniversityRan2024 to 2025Enrolled57ConditionsRheumatic Diseases, Temporomandibular Joint Dysfunction, Manuel TherapyArmsexercises
3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Kübra AktaşGraduate Education Institute, Master's Program in Physiotherapy and Rehabilitation, SANKO University, Gaziantep, Turkey.ORCID https://orcid.org/0009-0002-1109-6135
Hakan PolatDepartment of Physiotherapy and Rehabilitation, Faculty of Health Sciences, SANKO University, Gaziantep, Turkey.ORCID https://orcid.org/0000-0002-3704-9081
Tuba MadenDepartment of Physiotherapy and Rehabilitation, Faculty of Health Sciences, Gaziantep University, Gaziantep, Turkey.ORCID https://orcid.org/0000-0001-8713-0825
Burhan Fatih KoçyiğitDepartment of Physical Medicine and Rehabilitation, Adana City Training and Research Hospital, University of Health Sciences, Adana, Turkey.ORCID https://orcid.org/0000-0002-6065-8002

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThis study aimed to compare the effects of soft tissue mobilization (STM) and joint mobilization (JM) on mandibular mobility, cervical joint position sense (JPS), jaw function and anxiety levels in individuals with rheumatoid arthritis (RA) and temporomandibular disorders (TMD).

methodsThis randomized controlled study included 57 patients with RA and TMD, who were allocated to three groups: STM group (n = 19), JM group (n = 19) and control group (CG; n = 19). Interventions were applied twice weekly for 6 weeks. Outcome measures included mandibular range of motion (ROM), jaw function assessed using the Jaw Functional Limitation Scale-20 (JFLS-20), cervical JPS using a CROM device, and anxiety levels using the Generalized Anxiety Disorder-7 (GAD-7) questionnaire. Statistical significance was set at p < 0.05.

resultsBoth intervention groups demonstrated significant improvements in mandibular mobility, jaw function, and anxiety compared to CG (p < 0.05), whereas the CG showed deterioration in mouth opening, protrusion and anxiety over time. In mandibular mobility, both STM and JM showed significant improvements across most parameters, with JM showing a more consistent pattern of improvement. Significant improvements in cervical JPS were observed in the STM group for flexion, extension, and left rotation, and in the JM group for flexion only. No significant differences were found between the intervention groups in jaw function or anxiety outcomes.

conclusionSoft tissue mobilization enhances cervical proprioception more effectively, whereas joint mobilization provides greater improvements in mandibular mobility. Both manual therapy techniques are effective, non-invasive and clinically applicable options for managing TMD in individuals with RA.

trial registrationClinicalTrials.gov: NCT07171671.

Indexed as

AnxietyArthritis, RheumatoidMandibleMusculoskeletal ManipulationsRange of Motion, ArticularTemporomandibular Joint DisordersAdultCervical VertebraeFemaleHumansMaleMiddle AgedProprioceptionTemporomandibular JointTreatment Outcomeanxietyjoint mobilizationmanual therapyproprioceptionrheumatoid arthritissoft tissue mobilizationtemporomandibular disorders

Identifiers

PMID42175667
PMCPMC13480797

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.