Observational studyMedicine2026
Propensity score matching analysis of the association between Helicobacter pylori infection and colorectal polyps: A case-control study.
Observational study in Medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
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Corrections and comments
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The association between Helicobacter pylori (H. pylori) infection and colorectal polyps remains controversial. This study was a retrospective observational study. A total of 1106 patients who underwent gastrointestinal endoscopy at the First People's Hospital of Fuyang from January 2021 to May 2023 were enrolled. Based on colonoscopic findings, patients were stratified into a colorectal polyp group (n = 401) and a control group (n = 705). Propensity score matching (PSM) was applied in a 1:1 ratio to balance baseline confounders. Conditional logistic regression evaluated the association between H. pylori infection and colorectal polyps. Before PSM, significant differences were observed in body mass index, age, male sex, alcohol consumption history, smoking history, diabetes mellitus, and hypertension between the colorectal polyp group and control group (P < .05). After PSM, 347 matched pairs were generated. Using the matched sample, conditional logistic regression analysis identified H. pylori infection as a risk factor for colorectal polyps (odds ratio = 1.65, 95% confidence interval [CI]: 1.17-2.33; P = .004). Receiver operating characteristic curve analysis yielded an area under the curve of 0.549 (95% CI: 0.506-0.592; P = .025) for H. pylori infection in predicting polyps. The application of PSM further validates the association between H. pylori infection and colorectal polyps. H. pylori infection alone demonstrates limited predictive utility for colorectal polyp risk.
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