Evidence map›Paper›PMID 42174764›Full record

ReviewPhytotherapy research : PTR2026

Pomegranate in Cancer Therapy: A Review of Anticancer Potential, Mechanisms and Clinical Challenges in Breast, Colon and Prostate Cancers.

Dusanka Kitic, Bojana Miladinovic, Milica Randjelovic, Agnieszka Szopa, Veronique Seidel, Javad Sharifi-Rad, William N Setzer, Daniela Calina

Abstract readReview
In one paragraph

Review in Phytotherapy research : PTR, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Dusanka KiticDepartment of Pharmacy, Faculty of Medicine, University of Niš, Nis, Serbia.
Bojana MiladinovicDepartment of Pharmacy, Faculty of Medicine, University of Niš, Nis, Serbia.
Milica RandjelovicDepartment of Pharmacy, Faculty of Medicine, University of Niš, Nis, Serbia.
Agnieszka SzopaDepartment of Medicinal Plant and Mushroom Biotechnology, Faculty of Pharmacy, Jagiellonian University Medical College, Kraków, Poland.ORCID https://orcid.org/0000-0002-6351-4047
Veronique SeidelNatural Products Research Laboratory, Strathclyde Institute of Pharmacy and Biomedical Sciences, University of Strathclyde, Glasgow, UK.
Javad Sharifi-RadUniversidad Espíritu Santo, Samborondón, Ecuador.ORCID https://orcid.org/0000-0002-7301-8151
William N SetzerAromatic Plant Research Center, Lehi, Utah, USA.ORCID https://orcid.org/0000-0002-3639-0528
Daniela CalinaDepartment of Clinical Pharmacy, University of Medicine and Pharmacy of Craiova, Craiova, Romania.ORCID https://orcid.org/0000-0002-1523-9116

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pomegranate ( Punica granatum L.) is a plant that has been used in traditional medicine for centuries and that has gain popularity in recent years as an anticancer dietary supplement. For the purpose of this review, a comprehensive literature search was performed to gather articles published between 1993 and 2021 and describing the therapeutic potential of pomegranate fruit extracts, juice, and seed oil on breast, colon, and prostate cancer. The results of the studies highlighted the fact that while the consumption of pomegranate has been associated with a number of beneficial effects on cancer, it still remains unclear which chemicals are responsible for such effects. It is hoped that this review will encourage further investigations on pomegranate in order to identify the compounds (or their metabolites) responsible for biological activity and unravel their mode(s) of action at the molecular level.

Indexed as

Antineoplastic Agents, PhytogenicBreast NeoplasmsColonic NeoplasmsLythraceaePlant ExtractsPomegranateProstatic NeoplasmsHumansMaleAntineoplastic Agents, PhytogenicPlant Extractsbreast cancercolon cancerpomegranateprostate cancerPunica granatum

Identifiers

PMID42174764
PMCPMC13436239

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.