Evidence map›Paper›PMID 42174551›Full record

Observational studyBMC medical education2026

Effects of the BOPPPS model combined with case-based learning on knowledge acquisition and learning engagement in undergraduate nursing students: a multi-cohort quasi-experimental study.

Yuda Fei, Yaning Zhang, Jie Cai, Mei Xu, Jing Huang, Bin Du

Abstract readObservational Study
In one paragraph

Observational study in BMC medical education, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Yuda FeiDepartment of Infection Control, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China.
Yaning ZhangDepartment of Infection Control, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China.
Jie CaiDepartment of Infection Control, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China.
Mei XuDepartment of Infection Control, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China.
Jing HuangDepartment of Infection Control, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China. huangjing6638@pumch.cn.
Bin DuDepartment of Medical ICU, State Key Laboratory of Complex Severe and Rare Diseases, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China. dubin98@gmail.com.

Funding

the National Education Science Planning Project CLA210281
6 · The paper itself

Abstract

backgroundHealthcare-Associated Infection (HAI) prevention is a crucial competency in nursing education but is often taught through didactic lectures with limited application. This study evaluated the effectiveness of combining the Bridge-in, Objective, Pre-assessment, Participatory Learning, Post-assessment, and Summary (BOPPPS) model with Case-Based Learning (CBL) for HAI education using a non-equivalent control group design.

methodsA quasi-experimental study with a historical control group was conducted over three consecutive academic years (2023-2025). Second-year nursing undergraduates enrolled in an elective HAI module participated. The 2023 cohort (control group, n = 21) received traditional lecture-based learning (LBL). The 2024 (n = 18) and 2025 (n = 25) cohorts (intervention group, total n = 43) received instruction redesigned using the BOPPPS framework with CBL. Knowledge acquisition was assessed via identical pre- and post-course tests, analyzed using analysis of covariance (ANCOVA) with pre-test scores as covariates. Post-course perceptions were measured using an 8-dimension, 5-point Likert-scale questionnaire. Data were analyzed following the Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) guidelines adapted for educational interventions.

resultsBaseline characteristics were comparable (pre-test score: LBL = 54.00 ± 6.49 vs. BOPPPS-CBL = 52.30 ± 7.11, p = 0.360, Cohen's d = 0.17). ANCOVA revealed that the BOPPPS-CBL group achieved significantly higher post-test scores after adjusting for baseline differences (adjusted mean = 87.19 vs. 73.61; mean difference = 13.58, 95% CI: 11.14-16.03, F(1,61) = 123.46, p < 0.001, partial eta-squared = 0.669). Within-group improvements were significant for both conditions (both p < 0.001). The intervention group reported significantly higher scores across all seven positive perception dimensions (all p < 0.001 after Bonferroni correction), including self-directed learning (4.07 ± 0.80 vs. 3.19 ± 0.68, Cohen's d = 1.15) and teacher-student interaction (3.98 ± 0.80 vs. 2.76 ± 0.94, Cohen's d = 1.43). Notably, they also reported higher perceived learning burden (3.98 ± 0.86 vs. 2.29 ± 0.96, p < 0.001, Cohen's d = 1.90). Sensitivity analyses showed consistent intervention effects across the 2024 and 2025 cohorts (cohort-by-interaction p = 0.737). Qualitative feedback highlighted enhanced knowledge application and autonomous learning skills.

conclusionsThe BOPPPS-CBL model appears to be effective in enhancing HAI knowledge acquisition and fostering positive learning engagement among undergraduate nursing students. The increased perceived cognitive effort may represent 'productive cognitive engagement' rather than 'productive germane load'. This structured, active learning strategy offers a promising approach for teaching critical infection control competencies, though resource implications and design limitations warrant consideration. Institutions adopting this model should ensure rigorous case design and faculty development.

Indexed as

Cross InfectionEducation, Nursing, BaccalaureateModels, EducationalProblem-Based LearningStudents, NursingCohort StudiesCurriculumEducational MeasurementFemaleHumansMaleYoung AdultBOPPPS modelCase-Based Learning (CBL)Healthcare-Associated Infection (HAI)Historical ControlInfection ControlNursing EducationProblem-Based LearningQuasi-ExperimentStudents, Nursing

Identifiers

PMID42174551
PMCPMC13374324

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.