Evidence map›Paper›PMID 42174549›Full record

ArticleBMC ophthalmology2026

Classification of diabetic macular edema cases based on optical coherence tomography images and evaluation of morphological features.

Berke Temel, Fatma Yulek, Inci Elif Erbahceci Timur, Zuhal Ozen Tunay, Bekir Cakir, Reyhan Ersoy, Nagihan Ugurlu

Abstract read
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Article in BMC ophthalmology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Berke TemelDepartment of Ophthalmology, Mugla Sitki Kocman University, Mugla, Turkey. berketemel@gmail.com.
Fatma YulekPrivate Ophthalmology Clinic, Ankara, Turkey.
Inci Elif Erbahceci TimurDepartment of Ophthalmology, Ankara City Hospital, Ankara, Turkey.
Zuhal Ozen TunayDepartment of Ophthalmology, TOBB Economy and Technology University, Ankara, Turkey.
Bekir CakirDepartment of Endocrinology and Metabolism Diseases, Ankara Yıldırım Beyazıt University, Ankara, Turkey.
Reyhan ErsoyDepartment of Endocrinology and Metabolism Diseases, Ankara Yıldırım Beyazıt University, Ankara, Turkey.
Nagihan UgurluDepartment of Ophthalmology, Ankara Yıldırım Beyazit Universitesi, Ankara, Turkey.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThis study aimed to classify DME morphologically using optical coherence tomography (OCT) and to assess the impact of selected OCT biomarkers on DME subtypes.

methodsOCT images of patients with DME categorized into three groups as diffuse macular edema (dME), cystoid macular edema (CME) and cystoid degeneration (CD). Presence of subretinal fluid (SRF), disorganization of inner retinal layers (DRIL), ellipsoid zone (EZ) damage, external limiting membrane (ELM) damage, exudates, hyperreflective dots (HRD), epiretinal membrane (ERM) and vitreomacular traction (VMT) were evaluated. The effect of OCT findings on DME type was examined and factors affecting visual acuity were evaluated in this retrospective, cross-sectional study.

results746 eyes of 538 patients were evaluated and 55.1% were in the CME group, 40.6% in dME and 3.8% in the CD group. It was observed that the integrity of ELM and EZ was impaired in 11.58% and 11.09%, respectively. When SRF, DRIL, HRD, exudates, VMT and ERM were examined, the rates of 16.7%, 19.23%, 28.83%, 54.40%, 2.76% and 15.8% were obtained, respectively. The CD group had the weakest visual acuity, while the dME group had the greatest (P < 0.001). While SRF, HRD, and exudates were most common in CME; DRIL, ELM and EZ damages were most common in the CD group (P < 0.001).

conclusionThe group with the lowest visual acuity and the most damage to the outer retinal layers is the CD group. Presence of SRF, DRIL, HRD, exudate and ERM are also among the reasons that decrease visual acuity in DME.

Indexed as

Diabetic RetinopathyMacular EdemaTomography, Optical CoherenceAgedCross-Sectional StudiesFemaleHumansMaleMiddle AgedRetrospective StudiesVisual AcuityCystoid degenerationCystoid macular edemaDiabetic macular edemaDiffuse macular edemaOptical coherence tomography

Identifiers

PMID42174549
PMCPMC13371649

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.