Evidence map›Paper›PMID 42174425›Full record

ArticleBMC cardiovascular disorders2026

Association between gut microbiota diet index and cardiovascular disease in US adults: a cross-sectional study of NHANES 2007-2018.

Yun Lu, Siyuan Cheng, Yunchen Han, Shaojie Han, Hao Zhang

Abstract read
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Article in BMC cardiovascular disorders, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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1citing papers in PubMed
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1 · What the graph read from it

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3 · Its place in the literature

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1 citing paper in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Yun LuCardiac Surgery Department, Xuzhou Central Hospital, Southeast University, Xuzhou, China.
Siyuan ChengSchool of Medicine, Jinan University, Guangzhou, China.
Yunchen HanSchool of Medicine, Jinan University, Guangzhou, China.
Shaojie HanSchool of Medicine, Jinan University, Guangzhou, China.
Hao ZhangDepartment of Cardiothoracic Surgery, Affiliated Hospital of Xuzhou Medical University, Xuzhou, China. zhanghao@xzhmu.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe Dietary Index for Gut Microbiota (DI-GM), a recently developed metric designed to evaluate diet quality in relation to gut microbiota, has an uncharted connection with cardiovascular diseases (CVD).

methodsWe collected cross-sectional data from 8,533 participants in the National Health and Nutrition Examination Survey (NHANES) conducted between 2007 and 2018. Cardiovascular disease (CVD) was defined as a combination of self-reported physician diagnoses and standardized medical status questionnaires. Dietary recall data were utilized to calculate the DI-GM), which includes components that are both beneficial and unfavorable to gut microbiota. All analyses incorporated NHANES sample weights, stratification, and primary sampling units to account for the complex multistage probability sampling design. Logistic regression and Restricted cubic splines (RCS) were employed to explore the associations among DI-GM, beneficial gut microbiota, and CVD.

resultsThe control group had significantly higher DI-GM and beneficial gut microbiota score than the disease group (p < 0.05). Inverse associations were observed between DI-GM, beneficial gut microbiota score and the prevalence of cardiovascular disease (OR = 0.93, 95% CI = 0.89-0.97; OR = 0.88, 95% CI = 0.83-0.92). Moreover, RCS showed a linear relationship between DI-GM and cardiovascular disease.Subgroup analysis revealed stronger inverse associations between DI-GM and CVD among older individuals or those with hypertension or diabetes.

conclusionsA higher DI-GM was associated with a lower prevalence of CVD. Future studies are supposed to validate these findings by employing longitudinal studies.

Indexed as

Cardiovascular DiseasesDiet, HealthyGastrointestinal MicrobiomeAdultAgedCross-Sectional StudiesFemaleHeart Disease Risk FactorsHumansMaleMiddle AgedNutrition SurveysNutritive ValuePrevalenceProtective FactorsRisk AssessmentCardiovascular diseasesCross-sectional studyDietary index for gut microbiotaNHANES

Identifiers

PMID42174425
PMCPMC13452121

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.