Evidence map›Paper›PMID 42174394›Full record

ArticleBiotechnology progress

Binding of bacteria to magnetic nanoparticles in suspension: Experiments and kinetic models.

Bowen J Houser, Camille A Bryner, Aaron D Rappleyea, Breckin L Forstrom, Alyson N Camacho, Justin B Wood, Roger G Harrison, Karine Chesnel, William G Pitt

Abstract read
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In one paragraph

Article in Biotechnology progress. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Bowen J HouserDepartment of Chemical and Biological Engineering, Brigham Young University, Provo, Utah, USA.
Camille A BrynerDepartment of Chemical and Biological Engineering, Brigham Young University, Provo, Utah, USA.
Aaron D RappleyeaDepartment of Chemical and Biological Engineering, Brigham Young University, Provo, Utah, USA.
Breckin L ForstromDepartment of Micro and Molecular Biology, Brigham Young University, Provo, Utah, USA.
Alyson N CamachoDepartment of Chemical and Biological Engineering, Brigham Young University, Provo, Utah, USA.
Justin B WoodDepartment of Chemistry and Biochemistry, Brigham Young University, Provo, Utah, USA.
Roger G HarrisonDepartment of Chemistry and Biochemistry, Brigham Young University, Provo, Utah, USA.ORCID 0000-0001-5244-7793
Karine ChesnelDepartment of Physics and Astronomy, Brigham Young University, Provo, Utah, USA.
William G PittDepartment of Chemical and Biological Engineering, Brigham Young University, Provo, Utah, USA.ORCID 0000-0002-6043-3452

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

With the rise of antimicrobial-resistant and multi-drug-resistant bacteria, the use of magnetic nanoparticles (MNPs) has become a promising tool for separation processes in conjunction with in vitro diagnostics for the rapid identification of bacterial species in various medical and biological fluids. However, there are few studies on the time required for MNPs to successfully capture and remove bacteria from suspensions. This study presents two mathematical models that describe the kinetics of bacterial capture using polydopamine-coated MNPs (pDA-MNPs) in phosphate-buffered saline. The model parameters are derived from data from the capture of Staphylococcus aureus, Staphylococcus epidermidis, and Streptococcus mutans, which exhibit high adherence to pDA-MNPs. Results show that during the first 3 min, bacterial capture and removal by magnetic particles show second-order kinetics overall, and first order each with respect to bacterial concentration and to magnetic particle concentration. At longer times, the data are better fit by a model of fast and slow parallel capture mechanisms. pDA-MNPs capture S. epidermidis faster than S. aureus, and capture S. mutans more slowly than the other bacterial species. Rate constants derived at very high bacterial concentrations (~10

Indexed as

Magnetite NanoparticlesIndolesKineticsPolymersStaphylococcus aureusStaphylococcus epidermidisStreptococcus mutansIndolesMagnetite NanoparticlespolydopaminePolymersadhesion kineticsbacterial adhesionbacterial separationcapture kineticsiron oxide magnetic nanoparticlespolydopamine

Identifiers

PMID42174394
PMCPMC13441371

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.