Evidence map›Paper›PMID 42174313›Full record

ArticleParasitology research2026

Molecular identification and phylogenetic analysis of Echinococcus vogeli Rausch & Bernstein, 1972 from Cuniculus paca Linnaeus, 1766 consumed in extractive reserves in Acre, Brazil.

F Bittencourt-Oliveira, T P Dias-Correia, L B Neves, P E F Teixeira, J C Moreira, T C Pereira, F B Almeida, R Rodrigues-Silva, J R Machado-Silva

Abstract read
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Article in Parasitology research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

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2 · The registry

The trial behind it

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3 · Its place in the literature

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0 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

9 authors.

F Bittencourt-OliveiraLaboratório de Referência Nacional em Hidatidose, Laboratório de Parasitologia Integrativa e Paleoparasitologia, Instituto Oswaldo Cruz, Fundação Oswaldo Cruz, Rio de Janeiro, Rio de Janeiro, Brasil.ORCID http://orcid.org/0000-0002-3900-9163
T P Dias-CorreiaLaboratório de Referência Nacional em Hidatidose, Laboratório de Parasitologia Integrativa e Paleoparasitologia, Instituto Oswaldo Cruz, Fundação Oswaldo Cruz, Rio de Janeiro, Rio de Janeiro, Brasil.ORCID http://orcid.org/0000-0002-2389-8496
L B NevesLaboratório de Referência Nacional em Hidatidose, Laboratório de Parasitologia Integrativa e Paleoparasitologia, Instituto Oswaldo Cruz, Fundação Oswaldo Cruz, Rio de Janeiro, Rio de Janeiro, Brasil.ORCID http://orcid.org/0000-0002-0733-6549
P E F TeixeiraInstituto Federal do Mato Grosso do Sul, Campo Grande, Mato Grosso do Sul, Brasil.ORCID http://orcid.org/0000-0001-9041-5266
J C MoreiraInstituto Federal do Acre, Xapuri, Acre, Brasil.ORCID http://orcid.org/0000-0003-1051-6521
T C PereiraLaboratório de Referência Nacional em Hidatidose, Laboratório de Parasitologia Integrativa e Paleoparasitologia, Instituto Oswaldo Cruz, Fundação Oswaldo Cruz, Rio de Janeiro, Rio de Janeiro, Brasil.ORCID http://orcid.org/0009-0000-7520-9085
F B AlmeidaLaboratório de Referência Nacional em Hidatidose, Laboratório de Parasitologia Integrativa e Paleoparasitologia, Instituto Oswaldo Cruz, Fundação Oswaldo Cruz, Rio de Janeiro, Rio de Janeiro, Brasil.ORCID http://orcid.org/0000-0002-1404-5846
R Rodrigues-SilvaLaboratório de Referência Nacional em Hidatidose, Laboratório de Parasitologia Integrativa e Paleoparasitologia, Instituto Oswaldo Cruz, Fundação Oswaldo Cruz, Rio de Janeiro, Rio de Janeiro, Brasil. rsilva@ioc.fiocruz.br.ORCID http://orcid.org/0000-0002-3341-9866
J R Machado-SilvaLaboratório de Referência Nacional em Hidatidose, Laboratório de Parasitologia Integrativa e Paleoparasitologia, Instituto Oswaldo Cruz, Fundação Oswaldo Cruz, Rio de Janeiro, Rio de Janeiro, Brasil.ORCID http://orcid.org/0000-0003-3085-0228

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hunting wild animals for consumption is a common practice in the Brazilian Amazon and contributes to the transmission of zoonotic diseases, including neotropical echinococcosis (NE), caused by Echinococcus vogeli and Echinococcus oligarthra. Despite the endemicity of E. vogeli in this region, molecular data on its genetic diversity remain limited. This study characterized E. vogeli isolates obtained from lowland pacas (Cuniculus paca) in extractive reserves located in Xapuri and Sena Madureira, Acre, Brazil, using mitochondrial (cox1) and nuclear (p29) markers. All 16 isolates were confirmed as E. vogeli. Analysis of cox1 sequences revealed high similarity with reference sequences from the Brazilian Amazon, low nucleotide divergence (0-0.55%), and the presence of four haplotypes, including shared haplotypes between the two study areas. In contrast, no intraspecific variation was observed in the p29 sequences. These findings indicate low genetic diversity and suggest a relatively homogeneous pattern among the analyzed isolates, which may reflect gene flow or retention of ancestral polymorphisms. This study expands the limited molecular dataset available for E. vogeli, including additional p29 sequence data for this species, a molecular marker that remains poorly represented for E. vogeli, and provides relevant insights into its transmission dynamics in Amazonian environments.

Indexed as

EchinococcosisEchinococcusGenetic VariationPhylogenyAnimalsBrazilCluster AnalysisDNA, HelminthDNA, MitochondrialHaplotypesMolecular Sequence DataSequence Analysis, DNADNA, HelminthDNA, MitochondrialBrazilCuniculus pacaEchinococcus vogeliGenetic diversityPCRPopulation genetics

Identifiers

PMID42174313
PMCPMC13375818

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.